Technology Process of 2-(Benzyloxy)-5-chloro-4-methoxy-3,6-dimethylbenzoic acid
There total 7 articles about 2-(Benzyloxy)-5-chloro-4-methoxy-3,6-dimethylbenzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
dimethyl sulfoxide;
at 90 - 100 ℃;
for 4.5h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sulfuryl chloride / diethyl ether / 16 h / 25 °C
2: 98 percent / potassium carbonate / acetone / 21 h / Heating
3: 66 percent / boron trichloride / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) RT, 4 h
4: 88 percent / potassium carbonate / acetone / 22 h / Heating
5: 80 percent / potassium hydroxide / dimethylsulfoxide / 4.5 h / 90 - 100 °C
With
potassium hydroxide; sulfuryl dichloride; boron trichloride; potassium carbonate;
In
diethyl ether; dichloromethane; dimethyl sulfoxide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 98 percent / potassium carbonate / acetone / 21 h / Heating
2: 66 percent / boron trichloride / CH2Cl2 / 1.) -78 deg C, 1 h, 2.) RT, 4 h
3: 88 percent / potassium carbonate / acetone / 22 h / Heating
4: 80 percent / potassium hydroxide / dimethylsulfoxide / 4.5 h / 90 - 100 °C
With
potassium hydroxide; boron trichloride; potassium carbonate;
In
dichloromethane; dimethyl sulfoxide; acetone;
