Gabapentin Ethyl Ester Hydrochloride

Base Information

Chemical Name:Gabapentin Ethyl Ester Hydrochloride
CAS No.:60175-04-4
Molecular Formula:C11H21NO2.ClH
Molecular Weight:235.754
Hs Code.:
Mol file:60175-04-4.mol

Synonyms:(1-(2-ethoxy-2-oxoethyl)cyclohexyl)methanaminium chloride;Gabapentin Ethyl Ester Hydrochloride;ethyl (1-(aminomethyl)cyclohexyl)acetate hydrochloride;

Suppliers and Price of Gabapentin Ethyl Ester Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
GabapentinEthylEsterHydrochloride
2.5g
$ 1190.00

Medical Isotopes, Inc.
Gabapentinethylesterhydrochloride
1 g
$ 1790.00

Crysdot
Ethyl2-(1-(aminomethyl)cyclohexyl)acetatehydrochloride 97%
5g
$ 1386.00

AK Scientific
Ethyl2-[1-(aminomethyl)cyclohexyl]acetatehydrochloride
5g
$ 1549.00

Total 5 raw suppliers

Chemical Property of Gabapentin Ethyl Ester Hydrochloride

Chemical Property:

Melting Point:155-158°C
PSA：52.32000
LogP:3.35110
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

GabapentinEthylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses As protected Gabapentin (G117250), Amino acid structurally related to γ-Aminobutyric Acid (GABA), Gabapentin Ethyl Ester Hydrochloride has been designed to cross the blood brain barrier. Used as an anticonvulsant.

Technology Process of Gabapentin Ethyl Ester Hydrochloride

There total 2 articles about Gabapentin Ethyl Ester Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 64-17-5
ethanol

: 60142-96-3
H-Gpn-OH

: 60175-04-4
ethyl (1-(aminomethyl)cyclohexyl)acetate hydrochloride

Guidance literature:: With thionyl chloride; for 3.33h; Reflux;
DOI:10.1016/j.bioorg.2013.06.007

Reference yield:

: 64-17-5
ethanol

: 60142-96-3
H-Gpn-OH

: 60175-04-4
ethyl (1-(aminomethyl)cyclohexyl)acetate hydrochloride

: 1-(aminomethyl)cyclohexaneacetic acid hydrochloride

Guidance literature:: With hydrogenchloride; In water; for 0.0833333h; pH=2; Reflux;
DOI:10.1016/j.molstruc.2010.03.067

Reference yield: 67.0%

: 877864-03-4
acetic acid 2-(2-hydroxyethyldithio)ethyl ester

: 60175-04-4
ethyl (1-(aminomethyl)cyclohexyl)acetate hydrochloride

: ethyl 2-(1-(3,12-dioxo-4,11-dioxa-7,8-dithia-2-azatridecyl)cyclohexyl)acetate

Guidance literature:: acetic acid 2-(2-hydroxyethyldithio)ethyl ester; trichloromethyl chloroformate; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 0.666667h;

ethyl (1-(aminomethyl)cyclohexyl)acetate hydrochloride; In dichloromethane;