8-Phenyl-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:8-Phenyl-1,2,3,4-tetrahydroquinoline
CAS No.:60640-18-8
Molecular Formula:C15H15N
Molecular Weight:209.291
Hs Code.:
DSSTox Substance ID:DTXSID001291745

Synonyms:8-phenyl-1,2,3,4-tetrahydroquinoline;60640-18-8;SCHEMBL6300471;DTXSID001291745;AKOS000200746;1,2,3,4-Tetrahydro-8-phenylquinoline

Suppliers and Price of 8-Phenyl-1,2,3,4-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8-Phenyl-1,2,3,4-tetrahydroquinoline

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:209.120449483
Heavy Atom Count:16
Complexity:220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C(=CC=C2)C3=CC=CC=C3)NC1

Technology Process of 8-Phenyl-1,2,3,4-tetrahydroquinoline

There total 8 articles about 8-Phenyl-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 605-04-9
8-phenylquinoline

: 60640-18-8
8-phenyl-1,2,3,4-tetrahydro-quinoline

Guidance literature:: With C₂₂H₂₅BN₃⁽¹⁺⁾*C₂₄BF₂₀^(1-); hydrogen; In dichloromethane; at 20 ℃; for 23h; under 760.051 Torr; Further stages; Schlenk technique;
DOI:10.1002/anie.201409250

Reference yield: 70.0%

: 635-46-1
1,2,3,4-tetrahydroisoquinoline

: 108-90-7
chlorobenzene

: 3297-76-5
1-phenyl-1,2,3,4-tetrahydroquinoline

: 60640-18-8
8-phenyl-1,2,3,4-tetrahydro-quinoline

Guidance literature:: With 2,2,6,6-tetramethylpiperidinyl-lithium; In diethyl ether; cyclohexane; at 25 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol302875x

Reference yield:

: 69956-10-1
8-phenyl-2,3,4,4a,5,6,7,8-octahydro-quinoline

: 60640-18-8
8-phenyl-1,2,3,4-tetrahydro-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: nitrobenzene / 10percent palladium on C / xylene / 240 h

2: hydrogen / platinum oxide / methanol / 2250.2 Torr

With hydrogen; nitrobenzene; platinum(IV) oxide; palladium on activated charcoal; In methanol; xylene;