7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one

Base Information

Chemical Name:7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one
CAS No.:61085-32-3
Molecular Formula:C17H15NO2S
Molecular Weight:297.378
Hs Code.:
DSSTox Substance ID:DTXSID70512721

Synonyms:61085-32-3;SCHEMBL11466343;DTXSID70512721;IVJWUKJUOPAVFI-UHFFFAOYSA-N;7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one;7-Benzoyl-3-methyl-3-methylthioindolin-2-one;7-Benzoyl-3-methyl-3-metylthioindolin-2-one

Suppliers and Price of 7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:297.08234989
Heavy Atom Count:21
Complexity:433

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C2=CC=CC(=C2NC1=O)C(=O)C3=CC=CC=C3)SC

Technology Process of 7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one

There total 4 articles about 7-Benzoyl-3-methyl-3-(methylsulfanyl)-1,3-dihydro-2H-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 507-40-4
tert-butylhypochlorite

: 40800-76-8
2-methylsulfanyl-propionic acid ethyl ester

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 61085-32-3
7-benzoyl-1,3-dihydro-3-methyl-3-(thiomethyl)-2H-indol-2-one

Guidance literature:: With hydrogenchloride; triethylamine; In dichloromethane;

Reference yield:

: 2-(2-Amino-3-benzoyl-phenyl)-2-methylsulfanyl-propionic acid ethyl ester

: 61085-32-3
7-benzoyl-1,3-dihydro-3-methyl-3-(thiomethyl)-2H-indol-2-one

Guidance literature:: With hydrogenchloride; In dichloromethane; for 1h; Yield given; Ambient temperature;
DOI:10.1021/jm00346a022

Reference yield:

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 61085-32-3
7-benzoyl-1,3-dihydro-3-methyl-3-(thiomethyl)-2H-indol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 95percent tert-butyl hypochlorite, 2.) Et₃N / 1.) CH₂Cl₂, from -70 to -65 deg C, 1 h, 2.) from -65 deg C to RT

2: 3 N aq. HCl / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; tert-butylhypochlorite; triethylamine; In dichloromethane;
DOI:10.1021/jm00346a022