Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]-

Base Information

Chemical Name:Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]-
CAS No.:61173-98-6
Molecular Formula:C₂₆H₂₃OPS
Molecular Weight:414.508
Hs Code.:
DSSTox Substance ID:DTXSID40486223

Synonyms:61173-98-6;Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]-;DTXSID40486223

Suppliers and Price of Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]-

Chemical Property:

XLogP3:6.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:414.12072352
Heavy Atom Count:29
Complexity:489

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(P(=O)(C2=CC=CC=C2)C3=CC=CC=C3)SC4=CC=CC=C4

Technology Process of Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]-

There total 10 articles about Phosphine oxide, diphenyl[2-phenyl-1-(phenylthio)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66164-48-5
diphenyl(1-(phenylthio)ethyl)phosphine oxide

: 61173-98-6
Diphenyl-(2-phenyl-1-phenylthioethyl)-phosphinoxid

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / MCPBA / CH₂Cl₂; tetrahydrofuran / -78 °C

2: 65 percent / Ac₂O, MsOH / CH₂Cl₂ / 192 h / 25 °C

3: 2) NH₄Cl / 1) THF, -18 deg C, 15 min; 2) H₂O, room temp., 18 h

With methanesulfonic acid; acetic anhydride; ammonium chloride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)88377-X

Reference yield:

: 84904-73-4
1-chloro-1-phenylthioethyl-diphenylphosphine oxide

: 61173-98-6
Diphenyl-(2-phenyl-1-phenylthioethyl)-phosphinoxid

Guidance literature:: Multi-step reaction with 5 steps

1: silica gel / ethyl acetate / 16 h

2: 1.) BuLi, TMEDA / 1.) THF

3: 74 percent / MCPBA / CH₂Cl₂; tetrahydrofuran / -78 °C

4: 65 percent / Ac₂O, MsOH / CH₂Cl₂ / 192 h / 25 °C

5: 2) NH₄Cl / 1) THF, -18 deg C, 15 min; 2) H₂O, room temp., 18 h

With n-butyllithium; methanesulfonic acid; N,N,N,N,-tetramethylethylenediamine; acetic anhydride; silica gel; ammonium chloride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; ethyl acetate;
DOI:10.1016/S0040-4039(00)88377-X

Reference yield:

: 31238-57-0
diphenyl(phenylthiomethyl)phosphine oxide

: 61173-98-6
Diphenyl-(2-phenyl-1-phenylthioethyl)-phosphinoxid

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) BuLi, TMEDA / 1.) THF

2: 74 percent / MCPBA / CH₂Cl₂; tetrahydrofuran / -78 °C

3: 65 percent / Ac₂O, MsOH / CH₂Cl₂ / 192 h / 25 °C

4: 2) NH₄Cl / 1) THF, -18 deg C, 15 min; 2) H₂O, room temp., 18 h

With n-butyllithium; methanesulfonic acid; N,N,N,N,-tetramethylethylenediamine; acetic anhydride; ammonium chloride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)88377-X