Cbz-D-phenylalaninol

Base Information Edit

Chemical Name:Cbz-D-phenylalaninol
CAS No.:58917-85-4
Molecular Formula:C17H19NO3
Molecular Weight:285.343
Hs Code.:29051990
DSSTox Substance ID:DTXSID40974418
Nikkaji Number:J2.391.913C
Wikidata:Q72516360
ChEMBL ID:CHEMBL164463
Mol file:58917-85-4.mol

Synonyms:58917-85-4;Z-D-Phenylalaninol;CBZ-D-PHENYLALANINOL;(R)-(+)-2-(Cbz-amino)-3-phenyl-1-propanol;N-Carbobenzoxy-D-phenylalaninol;benzyl N-[(2R)-1-hydroxy-3-phenylpropan-2-yl]carbamate;(R)-(+)-2-(Benzyloxycarbonylamino)-3-phenyl-1-propanol;CHEMBL164463;MFCD00191193;N-Cbz-D-phenylalaninol;(R)-2-(Z-Amino)-3-phenyl-1-propanol;D-PHE-OL;Z-D-Phenylalaninol, 97%;(R)-benzyl 1-hydroxy-3-phenylpropan-2-ylcarbamate;SCHEMBL2482903;DTXSID40974418;WPOFMMJJCPZPAO-MRXNPFEDSA-N;n-benzyloxycarbonyl-d-phenylalaninol;BDBM50139464;AKOS015888140;CS-W012230;AC-23784;AS-31048;(R)-N-Cbz-2-amino-3-phenyl-1-propanol;C1609;EN300-7390052;(R)-N-Carbobenzoxy-2-amino-3-phenyl-1-propanol;A832073;benzyl((2R)-1-hydroxy-3-phenylpropan-2-yl)carbamate;Benzyl [(2R)-1-hydroxy-3-phenyl-2-propanyl]carbamate;(R)-(+)-2-BENZYLOXYCARBONYLAMINO-3-PHENYL-1-PROPANOL;Benzyl hydrogen (1-hydroxy-3-phenylpropan-2-yl)carbonimidate;((R)-1-Hydroxymethyl-2-phenyl-ethyl)-carbamic acid benzyl ester;Z-D-phenylalaninol, puriss., >=99.0% (sum of enantiomers, HPLC);N-[(2R)-1-hydroxy-3-phenylpropan-2-yl]carbamic acid (phenylmethyl) ester

Suppliers and Price of Cbz-D-phenylalaninol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-D-phenylalaninol
5g
$ 389.00

TRC
Z-D-Phenylalaninol
5g
$ 90.00

TCI Chemical
N-Carbobenzoxy-D-phenylalaninol >97.0%(HPLC)
1g
$ 43.00

TCI Chemical
N-Carbobenzoxy-D-phenylalaninol >97.0%(HPLC)
5g
$ 125.00

Sigma-Aldrich
Z-D-Phenylalaninol 97%
5g
$ 150.00

Medical Isotopes, Inc.
Z-D-Phenylalaninol
1 g
$ 350.00

Iris Biotech GmbH
Z-D-Phenylalaninol
25 g
$ 351.00

Iris Biotech GmbH
Z-D-Phenylalaninol
5 g
$ 101.25

Frontier Specialty Chemicals
Cbz-D-phenylalaninol 98%
5g
$ 188.00

Frontier Specialty Chemicals
Cbz-D-phenylalaninol 98%
1g
$ 47.00

Total 86 raw suppliers

Chemical Property of Cbz-D-phenylalaninol Edit

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Vapor Pressure:2.23E-10mmHg at 25°C
Melting Point:92-95 °C
Refractive Index:42 ° (C=2, MeOH)
Boiling Point:489 °C at 760 mmHg
PKA:11.86±0.46(Predicted)
Flash Point:249.6 °C
PSA：58.56000
Density:1.175 g/cm³
LogP:2.90730
Storage Temp.:Store at 0-5°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:285.13649347
Heavy Atom Count:21
Complexity:296

Purity/Quality:

99% ^*data from raw suppliers

Z-D-phenylalaninol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-24/25-37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(CO)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:C1=CC=C(C=C1)C[C@H](CO)NC(=O)OCC2=CC=CC=C2
Uses Z-D-Phenylalaninol is used in the synthesis of aminophenylpropanyl phosphate derivatives which has pin1 inhibitory activity.

Technology Process of Cbz-D-phenylalaninol

There total 23 articles about Cbz-D-phenylalaninol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%