8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Base Information

Chemical Name:8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE
CAS No.:612065-26-6
Molecular Formula:C20H17N3O5S
Molecular Weight:411.43100
Hs Code.:
Mol file:612065-26-6.mol

Synonyms:8-Benzenesulfonyl-6-(4-nitrophenylamino)-2,3-dihydro-1H-indolizin-5-one;

Suppliers and Price of 8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE 95.00%
5MG
$ 500.19

Total 2 raw suppliers

Chemical Property of 8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Chemical Property:

Vapor Pressure:7.98E-18mmHg at 25°C
Boiling Point:670.2oC at 760 mmHg
Flash Point:359.1oC
PSA：122.37000
Density:1.51g/cm3
LogP:4.95610

Purity/Quality:

97% ^*data from raw suppliers

8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

There total 4 articles about 8-BENZENESULFONYL-6-(4-NITROPHENYLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 100-01-6,104810-17-5
4-nitro-aniline

: 185198-44-1
trifluoromethanesulfonic acid 8-phenylsulfonyl-5-oxo-1,2,3,5-tetrahydroindolizin-6-yl ester

: 612065-26-6
8-benzenesulfonyl-6-(4-nitro-phenylamino)-2,3-dihydro-1H-indolizin-5-one

Guidance literature:: With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃;
DOI:10.1021/jo0511492

Reference yield:

: 5535-48-8
PVS

: 612065-26-6
8-benzenesulfonyl-6-(4-nitro-phenylamino)-2,3-dihydro-1H-indolizin-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: Rh(II)

2: Et₃N

3: 63 percent / 9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene; cesium carbonate / tris(dibenzylideneacetone)palladium⁽⁰⁾ / dioxane / 100 °C

With caesium carbonate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; rhodium⁽²⁺⁾; In 1,4-dioxane;
DOI:10.1021/jo0511492

Reference yield:

: 185198-40-7
1-(2-benzenesulfonyl-2-diazoacetyl)pyrrolidin-2-one

: 612065-26-6
8-benzenesulfonyl-6-(4-nitro-phenylamino)-2,3-dihydro-1H-indolizin-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: Rh(II)

2: Et₃N

3: 63 percent / 9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene; cesium carbonate / tris(dibenzylideneacetone)palladium⁽⁰⁾ / dioxane / 100 °C

With caesium carbonate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; rhodium⁽²⁺⁾; In 1,4-dioxane;
DOI:10.1021/jo0511492