Benzamide, N-(2,5-diphenyl-2H-1,2,3-triazol-4-yl)-

Base Information

• Chemical Name: Benzamide, N-(2,5-diphenyl-2H-1,2,3-triazol-4-yl)-
• CAS No.: 61308-15-4
• Molecular Formula: C21H16N4O
• Molecular Weight: 340.384
• DSSTox Substance ID: DTXSID50472298
• Nikkaji Number: J324.848H
• Wikidata: Q82301143
• Mol file: 61308-15-4.mol

Synonyms:61308-15-4;Benzamide, N-(2,5-diphenyl-2H-1,2,3-triazol-4-yl)-;DTXSID50472298

Chemical Property of Benzamide, N-(2,5-diphenyl-2H-1,2,3-triazol-4-yl)-

Chemical Property:

• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 340.13241115
• Heavy Atom Count: 26
• Complexity: 453

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NN(N=C2NC(=O)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of Benzamide, N-(2,5-diphenyl-2H-1,2,3-triazol-4-yl)-

There total 11 articles about Benzamide, N-(2,5-diphenyl-2H-1,2,3-triazol-4-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(Z)-phenylhydrazone 3-benzoyl-5-phenyl-1,2,4-oxadiazole (59785-50-1,74675-58-4,74675-59-5) → 2,5-diphenyl-4-benzoylamino-1,2,3-triazole (61308-15-4)

Guidance literature:

With [p-Xyl-(bim)2][NTf₂]2; at 89.84 ℃; for 8h; Ionic liquid;

DOI:10.1002/ejoc.201100763

Reference yield: 91.0%

(E)-3-benzoyl-5-pgenyl-1,2,4-oxadiazole phenylhydrazone (59785-50-1,74675-58-4,74675-59-5) → 2,5-diphenyl-4-benzoylamino-1,2,3-triazole (61308-15-4)

Guidance literature:

With copper diacetate; In methanol; at 39.84 ℃; for 8h; Further Variations:; Reagents; Product distribution;

DOI:10.1002/poc.1327

Reference yield: 74.3%

(E)-3-benzoyl-5-pgenyl-1,2,4-oxadiazole phenylhydrazone (59785-50-1,74675-58-4,74675-59-5) → 2,5-diphenyl-4-benzoylamino-1,2,3-triazole (61308-15-4) + (Z)-phenylhydrazone 3-benzoyl-5-phenyl-1,2,4-oxadiazole (59785-50-1,74675-58-4,74675-59-5)

Guidance literature:

With copper dichloride; In methanol; at 39.94 ℃; for 4h; Ionic liquid;

DOI:10.1016/j.tet.2008.09.055

upstream raw materials:

(E)-3-benzoyl-5-pgenyl-1,2,4-oxadiazole phenylhydrazone

phenyl(5-phenyl-1,2,4-oxadiazol-3-yl)methanone

1-Methyl-1-phenylhydrazine

(Z)-phenylhydrazone 3-benzoyl-5-phenyl-1,2,4-oxadiazole

Downstream raw materials:

4-amino-2,5-diphenyl-2H-1,2,3-triazole