3-Isoquinolin-1-yl-1-phenylpropan-1-one

Base Information

Chemical Name:3-Isoquinolin-1-yl-1-phenylpropan-1-one
CAS No.:10293-89-7
Molecular Formula:C18H15 N O
Molecular Weight:261.3178
Hs Code.:
NSC Number:101034
DSSTox Substance ID:DTXSID00295297
Wikidata:Q82035149
Mol file:10293-89-7.mol

Synonyms:10293-89-7;3-isoquinolin-1-yl-1-phenylpropan-1-one;NSC101034;DTXSID00295297;NSC-101034;3-(1-isoquinolinyl)-1-phenyl-1-propanone

Suppliers and Price of 3-Isoquinolin-1-yl-1-phenylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Isoquinolin-1-yl-1-phenylpropan-1-one

Chemical Property:

Vapor Pressure:1.63E-08mmHg at 25°C
Boiling Point:456.3°C at 760 mmHg
Flash Point:233.9°C
Density:1.158g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:261.115364102
Heavy Atom Count:20
Complexity:321

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CCC2=NC=CC3=CC=CC=C32

Technology Process of 3-Isoquinolin-1-yl-1-phenylpropan-1-one

There total 6 articles about 3-Isoquinolin-1-yl-1-phenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 119-65-3
isoquinoline

: 29526-96-3
1-phenylcyclopropan-1-ol

: 10293-89-7
3-(isoquinolin-1-yl)-1-phenylpropan-1-one

Guidance literature:: With dipotassium peroxodisulfate; In water; dimethyl sulfoxide; at 70 ℃; for 12h; Inert atmosphere;
DOI:10.1002/ejoc.202000289

Reference yield:

: 412297-61-1
3-phenyl-pyrrolo[2,1-a]isoquinoline-2-carboxylic acid amide

: 10293-89-7
3-(isoquinolin-1-yl)-1-phenylpropan-1-one

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja01111a022

Reference yield:

: 844-25-7,55839-33-3
2-benzoyl-1-cyano-1,2-dihydroisoquinoline

: 10293-89-7
3-(isoquinolin-1-yl)-1-phenylpropan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane; phenyl lithium; diethyl ether / Reagens 4: Acrylonitril, Reagens 5: festes CO₂, Reagens 6: H₂O

2: aqueous hydrochloric acid

With 1,4-dioxane; hydrogenchloride; diethyl ether; phenyllithium;
DOI:10.1021/ja01111a022