Butanoic acid, 2-chloro-3-oxo-, (2E)-3-phenyl-2-propenyl ester

Base Information

• Chemical Name: Butanoic acid, 2-chloro-3-oxo-, (2E)-3-phenyl-2-propenyl ester
• CAS No.: 61363-95-9
• Molecular Formula: C13H13ClO3
• Molecular Weight: 252.697
• Mol file: 61363-95-9.mol

Synonyms:

Chemical Property of Butanoic acid, 2-chloro-3-oxo-, (2E)-3-phenyl-2-propenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Butanoic acid, 2-chloro-3-oxo-, (2E)-3-phenyl-2-propenyl ester

There total 1 articles about Butanoic acid, 2-chloro-3-oxo-, (2E)-3-phenyl-2-propenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(E)-(3-phenylallyl) 3-oxo-butyrate (61363-91-5) → 2-Chloro-3-oxo-butyric acid (E)-3-phenyl-allyl ester (61363-95-9)

Guidance literature:

With N-chloro-succinimide; Phenylselenyl chloride; 4 A molecular sieve; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tet.2005.12.072

Reference yield: 67.0%

2-Chloro-3-oxo-butyric acid (E)-3-phenyl-allyl ester (61363-95-9) → C11H10ClNO3 (74959-12-9)

Guidance literature:

With hydrogenchloride; isopentyl nitrite; In diethyl ether; for 8h; Ambient temperature;

Reference yield:

2-Chloro-3-oxo-butyric acid (E)-3-phenyl-allyl ester (61363-95-9) → 2-(4-chloro-phenyl)-3c-phenyl-(3ar)-2,3,3a,4-tetrahydro-furo[3,4-c]pyrazol-6-one (61364-04-3,80553-51-1)

Guidance literature:

Multi-step reaction with 2 steps

2: Et₃N / toluene / 3 h / Heating

With triethylamine; In toluene;

DOI:10.1021/jo00428a027

upstream raw materials:

(E)-(3-phenylallyl) 3-oxo-butyrate

Downstream raw materials:

chloro-(4-chloro-phenylhydrazono)-acetic acid 3t-phenyl-allyl ester

C₁₁H₁₀ClNO₃

<3α,3aα>-3-phenylfuro<3,4-c>isoxazoline

(4R,5S)-4-Hydroxymethyl-5-phenyl-4,5-dihydro-isoxazole-3-carboxylic acid