N-(2-methylquinolin-8-yl)benzamide

Base Information

Chemical Name:N-(2-methylquinolin-8-yl)benzamide
CAS No.:61388-91-8
Molecular Formula:C17H14N2O
Molecular Weight:262.311
Hs Code.:
DSSTox Substance ID:DTXSID30586089
Nikkaji Number:J2.872.413F
Wikidata:Q82478133

Synonyms:N-(2-methylquinolin-8-yl)benzamide;61388-91-8;Benzamide, N-(2-methyl-8-quinolinyl)-;DTXSID30586089;HMS3456M22;STL203256;AKOS001533574;MCULE-9843879190;NCGC00277370-01;AB01281965-01

Suppliers and Price of N-(2-methylquinolin-8-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-(2-methylquinolin-8-yl)benzamide

Chemical Property:

PSA：45.48000
LogP:4.17950
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:262.110613074
Heavy Atom Count:20
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(C=CC=C2NC(=O)C3=CC=CC=C3)C=C1

Technology Process of N-(2-methylquinolin-8-yl)benzamide

There total 3 articles about N-(2-methylquinolin-8-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 18978-78-4
2-methyl-8-aminoquinoline

: 98-88-4
benzoyl chloride

: 61388-91-8
N-(2-methylquinolin-8-yl)benzamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/adsc.201700471

Reference yield: 92.0%

: 18978-78-4
2-methyl-8-aminoquinoline

: 65-85-0,8013-63-6
benzoic acid

: 61388-91-8
N-(2-methylquinolin-8-yl)benzamide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1055/s-0037-1610212

Reference yield:

: 65-85-0,8013-63-6
benzoic acid

: 61388-91-8
N-(2-methylquinolin-8-yl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide; dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

2: triethylamine / dichloromethane / 0 - 20 °C / Sealed tube; Schlenk technique

With oxalyl dichloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/ejoc.201701150