6-Methyl-2-phenyl-4,5-pyrimidinedicarboxylic acid dimethyl ester

Base Information

Chemical Name:6-Methyl-2-phenyl-4,5-pyrimidinedicarboxylic acid dimethyl ester
CAS No.:61416-99-7
Molecular Formula:C15H14N2O4
Molecular Weight:286.28300
Hs Code.:2933599090
Mol file:61416-99-7.mol

Synonyms:dimethyl 2-phenyl-6-methylpyrimidine-4,5-dicarboxylate;6-methyl-2-phenyl-pyrimidine-4,5-dicarboxylic acid dimethyl ester;Dimethyl 6-methyl-2-phenyl-4,5-pyrimidinedicarboxylate;4,5-Pyrimidinedicarboxylic acid,6-methyl-2-phenyl-,dimethyl ester;

Suppliers and Price of 6-Methyl-2-phenyl-4,5-pyrimidinedicarboxylic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 6-Methyl-2-phenyl-4,5-pyrimidinedicarboxylic acid dimethyl ester

Chemical Property:

PSA：78.38000
LogP:2.02520

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-Methyl-2-phenyl-4,5-pyrimidinedicarboxylic acid dimethyl ester

There total 6 articles about 6-Methyl-2-phenyl-4,5-pyrimidinedicarboxylic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 762-42-5
dimethyl acetylenedicarboxylate

: N-(methoxycarbonyl)-N'-acetylbenzamidine

: 61416-99-7
dimethyl 2-phenyl-6-methylpyrimidine-4,5-dicarboxylate

Guidance literature:: In 1,2-dichloro-benzene; at 150 ℃; 24-28 h;
DOI:10.1021/jo952106w

Reference yield: 45.0%

: 762-42-5
dimethyl acetylenedicarboxylate

: 1-(tert-butoxycarbonyl)-2-phenyl-4-(dimethylamino)-1,3-diaza-1,3-pentadiene

: 61416-99-7
dimethyl 2-phenyl-6-methylpyrimidine-4,5-dicarboxylate

Guidance literature:: In toluene; Heating;
DOI:10.1021/jo952106w

Reference yield:

: 1670-14-0
benzamidine monohydrochloride

: 61416-99-7
dimethyl 2-phenyl-6-methylpyrimidine-4,5-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / sodium hydroxide / H₂O; tetrahydrofuran / 1 h / 0 °C

2: tetrahydrofuran / 5 h / Heating

3: 45 percent / toluene / Heating

With sodium hydroxide; In tetrahydrofuran; water; toluene;
DOI:10.1021/jo952106w