(3,4-Dichlorophenyl)methylidenehydrazine

Base Information

• Chemical Name: (3,4-Dichlorophenyl)methylidenehydrazine
• CAS No.: 61428-00-0
• Molecular Formula: C7H6Cl2N2
• Molecular Weight: 189.044
• DSSTox Substance ID: DTXSID40391186
• Mol file: 61428-00-0.mol

Synonyms:61428-00-0;Benzaldehyde, 3,4-dichloro-, hydrazone;[(3,4-DICHLOROPHENYL)METHYLIDENE]HYDRAZINE;(3,4-dichlorophenyl)methylidenehydrazine;SCHEMBL8462042;DTXSID40391186

Chemical Property of (3,4-Dichlorophenyl)methylidenehydrazine

Chemical Property:

• Boiling Point: 310.1±52.0 °C(Predicted)
• PSA: 38.38000
• Density: 1.38±0.1 g/cm3(Predicted)
• LogP: 2.98630
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 187.9908036
• Heavy Atom Count: 11
• Complexity: 149

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C=NN)Cl)Cl

Technology Process of (3,4-Dichlorophenyl)methylidenehydrazine

There total 1 articles about (3,4-Dichlorophenyl)methylidenehydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3,4-dichlorobenzaldehyde (6287-38-3) → (3,4-Dichlor-benzyliden)-hydrazin (61428-00-0)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 3h;

DOI:10.1039/c6ob02074g

Reference yield: 88.0%

Togni's reagent II (887144-94-7) + (3,4-Dichlor-benzyliden)-hydrazin (61428-00-0) → 1,2-dichloro-4-(2,2,2-trifluoroethyl)benzene (1099597-16-6)

Guidance literature:

With cesium fluoride; potassium hydroxide; In water; acetonitrile; at 20 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1002/chem.201902818

Reference yield: 85.0%

toluene-4-sulfonic acid phenyl ester (640-60-8) + (3,4-Dichlor-benzyliden)-hydrazin (61428-00-0) → 1,2-dichloro-4-(phenylmethyl)benzene (64543-53-9)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,8-diazabicyclo[5.4.0]undec-7-ene; trimethylphosphane; In tetrahydrofuran; at 110 ℃; for 12h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/acscatal.8b01224

upstream raw materials:

3,4-dichlorobenzaldehyde

Downstream raw materials:

C₁₁H₁₃Cl₂N₃O

C₁₂H₁₅Cl₂N₃O

1,2-dichloro-4-(fluoromethyl)benzene

1,2-dichloro-4-(phenylmethyl)benzene