640-60-8Relevant articles and documents
Unprecedented regioselective tosylation studies of 2-ene 4,5,6,7-polyol derived from d-ribose
Dhonthulachitty, Chiranjeevi,Kothakapu, Sridhar Reddy,Neella, Chandra Kiran
, p. 2434 - 2436 (2016)
[DMAPTs]+Cl- was employed as a new facile unprecedented regioselective tosylation procedure for 2-ene 4,5,6,7-polyol derived from d-ribose involving chemoselective ditosylation and regioselective allylic tosyl hydrolysis upon work up with sat. NaCl (brine) solution in a single operation by minimizing the side products obtained under classical regioselective tosylation. The same reagent was also employed for rapid quantitative base free tosylation of aniline, phenol, and 2-naphthol. A tentative mechanism for the afore said regioselective tosylation was also proposed.
Identification of organophosphorus simulants for the development of next-generation detection technologies
Ellaby, Rebecca J.,Clark, Ewan R.,Allen, Nyasha,Taylor, Faith R.,Ng, Kendrick K. L.,Dimitrovski, Milan,Chu, Dominique F.,Mulvihill, Daniel P.,Hiscock, Jennifer R.
, p. 2008 - 2014 (2021/03/16)
Organophosphorus (OP) chemical warfare agents (CWAs) represent an ongoing threat but the understandable widespread prohibition of their use places limitations on the development of technologies to counter the effects of any OP CWA release. Herein, we describe new, accessible methods for the identification of appropriate molecular simulants to mimic the hydrogen bond accepting capacity of the PO moiety, common to every member of this class of CWAs. Using the predictive methodologies developed herein, we have identified OP CWA hydrogen bond acceptor simulants for soman and sarin. It is hoped that the effective use of these physical property specific simulants will aid future countermeasure developments.
Nickel-Catalyzed Photodehalogenation of Aryl Bromides
Higginson, Bradley,Sanjosé-Orduna, Jesus,Gu, Yiting,Martin, Ruben
supporting information, p. 1633 - 1636 (2021/04/23)
Herein, we describe a Ni-catalyzed photodehalogenation of aryl bromides under visible-light irradiation that utilizes tetrahydrofuran as hydrogen source. The protocol obviates the need for exogeneous amine reductants or photocatalysts and is characterized by its simplicity and broad scope, including challenging substrate combinations.
The Synthesis and Catalytic Activity of New Mixed NHC-Phosphite Nickel(0) Complexes
Dorta, Reto,Duczynski, Jeremy,Moggach, Stephen A.,Sobolev, Alexandre N.,Stewart, Scott G.
supporting information, (2020/01/21)
Herein we describe the synthesis and isolation of the first low-valent NHC-phosphite nickel complexes of general formula Ni(NHC)[P(OAr)3]2. These three-coordinate Ni(0) compounds were fully characterized, including by X-ray crystallography that highlighted their trigonal planar geometry. The representative complex Ni(IMes)[P(OPh)3]2 was used to show that a phosphite ligand is readily substituted in the presence of an aldehyde or nitrile. These stoichiometric studies then led to an investigation of their catalytic properties in the Suzuki-Miyaura cross-coupling reactions between aryl tosylates and aryl boronic acids, a first for such a NHC-Ni catalyst. Finally, mechanistic investigations led to the isolation of a well-defined oxidative addition product.