1-methylquinoline-2,4(1H,3H)-dione

Base Information

• Chemical Name: 1-methylquinoline-2,4(1H,3H)-dione
• CAS No.: 61469-95-2
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.187
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID80399348
• Wikidata: Q82201839
• Mol file: 61469-95-2.mol

Synonyms:1-methylquinoline-2,4(1H,3H)-dione;61469-95-2;1-methylquinoline-2,4-dione;1-methyl-1,2,3,4-tetrahydroquinoline-2,4-dione;AKOS BBS-00002518;N-methylquinoline-2,4-dione;F2130-0036;SCHEMBL8054672;DTXSID80399348;BBL029477;STK392482;AKOS000271398;1-methyl-2,4(1H,3H)-quinolinedione;BB 0219027;CS-0133048;EN300-41514;Z336080132

Chemical Property of 1-methylquinoline-2,4(1H,3H)-dione

Chemical Property:

• PSA: 37.38000
• LogP: 1.30080
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 175.063328530
• Heavy Atom Count: 13
• Complexity: 249

Purity/Quality:

98%Min ^*data from raw suppliers

1-methyl-1,2,3,4-tetrahydroquinoline-2,4-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN1C(=O)CC(=O)C2=CC=CC=C21

Technology Process of 1-methylquinoline-2,4(1H,3H)-dione

There total 17 articles about 1-methylquinoline-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Methylanthranilic acid (119-68-6) → 1-methyl-1H-quinoline-2,4-dione (61469-95-2)

Guidance literature:

With acetic anhydride; acetic acid;

DOI:10.1021/ja01213a041

Reference yield:

3-benzyl-4-hydroxy-1-methylquinolin-2(1H)-one (72587-96-3) → 1-methyl-1H-quinoline-2,4-dione (61469-95-2)

Guidance literature:

With aluminium trichloride; phenol; at 250 ℃;

DOI:10.1007/BF00902404

Reference yield:

→ 1-methyl-1H-quinoline-2,4-dione (61469-95-2)

Guidance literature:

With hydrogenchloride; at 120 ℃;

upstream raw materials:

4-ethoxy-1-methyl-1H-quinolin-2-one

3-benzyl-4-hydroxy-1-methylquinolin-2(1H)-one

N-methyl-4-methoxyquinolin-2(1H)-one

4-acetyloxy-1-methyl-1H-quinoline-2-chromone

Downstream raw materials:

4-Benzoyloxy-1-methyl-1,2-dihydro-chinolin-2-on

4-hydrazino-1-methyl-2(1H)-quinolinone

3-diazo-1-methylquinoline-2,4(1H,3H)-dione

2-amino-4-(4-chlorophenyl)-6-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carbonitrile