6-Methylpyrazolo[1,5-a]pyrimidine

Base Information

Chemical Name:6-Methylpyrazolo[1,5-a]pyrimidine
CAS No.:61578-00-5
Molecular Formula:C7H7N3
Molecular Weight:133.15100
Hs Code.:2933990090
ChEMBL ID:CHEMBL3246700
DSSTox Substance ID:DTXSID20509525
Wikidata:Q82367160
Mol file:61578-00-5.mol

Synonyms:6-methylpyrazolo[1,5-a]pyrimidine;61578-00-5;SCHEMBL9729655;CHEMBL3246700;DTXSID20509525;AKOS005169143;AB62554;CCG-321703;CS-0282169;C90973;EN300-232145

Suppliers and Price of 6-Methylpyrazolo[1,5-a]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 6-Methylpyrazolo[1,5-a]pyrimidine

Chemical Property:

PSA：30.19000
LogP:1.03770
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:133.063997236
Heavy Atom Count:10
Complexity:126

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CN2C(=CC=N2)N=C1

Technology Process of 6-Methylpyrazolo[1,5-a]pyrimidine

There total 2 articles about 6-Methylpyrazolo[1,5-a]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 62055-46-3
3-ethoxy-2-methylacrolein

: 1225387-53-0
3⁽⁵⁾-aminopyrazole

: 61578-00-5
6-methylpyrazolo[1,5-a]pyrimidine

Guidance literature:: In acetic acid; for 3h; Heating;

Reference yield:

: 61578-00-5
6-methylpyrazolo[1,5-a]pyrimidine

Guidance literature:: /BRN= 609898/ ,H2/Pd-C (vgl.J.Med.Chem.20,000<1977>,presented at the 168th Nat.Meeting of the Am.Chem.Soc.,Atlantic City,N.J.1974,MEDI 42);
DOI:10.1021/jm00213a014

Reference yield:

: 61578-00-5
6-methylpyrazolo[1,5-a]pyrimidine

: N-(1-(4-methoxyphenyl)propyl)-6-methylpyrazolo[1,5-a]-pyrimidine-3-sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 2 h / 80 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C

With chlorosulfonic acid; N-ethyl-N,N-diisopropylamine; In acetonitrile;
DOI:10.1021/acs.jmedchem.7b00709