(Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one

Base Information

Chemical Name:(Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one
CAS No.:76988-00-6
Molecular Formula:C10H7ClN2OS
Molecular Weight:238.697
Hs Code.:
NSC Number:139706

Synonyms:NSC139706;SMSF0005710;AKOS002209518;CB01167;NSC-139706;BIM-0000166.P001;SR-01000206986;SR-01000206986-1;(Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one;F1950-0204;76988-00-6

Suppliers and Price of (Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one

Chemical Property:

Vapor Pressure:2.82E-07mmHg at 25°C
Boiling Point:420.4°Cat760mmHg
Flash Point:208.1°C
Density:1.49g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:237.9967617
Heavy Atom Count:15
Complexity:332

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=C2C(=O)N=C(S2)N)Cl
Isomeric SMILES:C1=CC(=CC=C1/C=C\2/C(=O)N=C(S2)N)Cl

Technology Process of (Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one

There total 4 articles about (Z)-2-amino-5-(4-chlorobenzylidene)thiazol-4(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 76979-35-6
2-methylthio-5-p-chlorophenylmethylene-thiazolinone-4

: 76988-00-6
5-(4-Chlorophenylmethylene)-2-imino-4-thiazolidinone

Guidance literature:: With ammonium carbonate; In butan-1-ol; Heating;

Reference yield: 77.0%

: 104-88-1
4-chlorobenzaldehyde

: 556-90-1
pseudothiohydantoin

: 76988-00-6
5-(4-Chlorophenylmethylene)-2-imino-4-thiazolidinone

Guidance literature:: With sodium acetate; acetic acid; at 160 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1080/00397910802323072

Reference yield:

: 6318-37-2,81154-18-9
5-(4-chlorobenzylidene)rhodanine

: 76988-00-6
5-(4-Chlorophenylmethylene)-2-imino-4-thiazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / NaOH / acetone; H₂O / 3 h / Ambient temperature

2: 85 percent / (NH₄)2CO₃ / butan-1-ol / Heating

With sodium hydroxide; ammonium carbonate; In water; acetone; butan-1-ol;