Bicyclo[4.2.0]octa-1,3,5-trien-7-amine

Base Information

Chemical Name:Bicyclo[4.2.0]octa-1,3,5-trien-7-amine
CAS No.:61599-85-7
Molecular Formula:C8H9N
Molecular Weight:119.166
Hs Code.:2921300090
DSSTox Substance ID:DTXSID20372953
Nikkaji Number:J90.165B
ChEMBL ID:CHEMBL4588319
Mol file:61599-85-7.mol

Synonyms:bicyclo[4.2.0]octa-1,3,5-trien-7-amine;61599-85-7;1-aminobenzocyclobutene;SCHEMBL2463276;CHEMBL4588319;DTXSID20372953;OVLLQUKHPTXIBH-UHFFFAOYSA-N;1,2-dihydrocyclobutabenzen-2-amine;AKOS006338580;BS-13167;EN300-188021;bicyclo[4.2.0]octa-1(6),2,4-trien-7-amine

Suppliers and Price of Bicyclo[4.2.0]octa-1,3,5-trien-7-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Bicyclo[4.2.0]octa-1,3,5-trien-7-amine
1g
$ 835.00

TRC
Bicyclo[4.2.0]octa-1,3,5-trien-7-amine
250mg
$ 420.00

Total 4 raw suppliers

Chemical Property of Bicyclo[4.2.0]octa-1,3,5-trien-7-amine

Chemical Property:

PSA：26.02000
LogP:1.94280
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:119.073499291
Heavy Atom Count:9
Complexity:111

Purity/Quality:

97% ^*data from raw suppliers

Bicyclo[4.2.0]octa-1,3,5-trien-7-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(C2=CC=CC=C21)N
Uses Bicyclo[4.2.0]octa-1,3,5-trien-7-amine exhibits norepinephrine methyltransferase inhibition.

Technology Process of Bicyclo[4.2.0]octa-1,3,5-trien-7-amine

There total 9 articles about Bicyclo[4.2.0]octa-1,3,5-trien-7-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21120-91-2
1-bromobenzocyclobutene

: 61599-85-7
bicyclo[4.2.0]octa-1,3,5-trien-7-amine

Guidance literature:: Multi-step reaction with 3 steps

2: KOH

3: H₂SO₄, NaN₃

With potassium hydroxide; sodium azide; sulfuric acid;

Reference yield:

: 163222-89-7,163222-90-0,14381-41-0
1,2-dihydrocyclobutabenzene-1-carboxylic acid

: 61599-85-7
bicyclo[4.2.0]octa-1,3,5-trien-7-amine

Guidance literature:: With sodium azide; chloroform; sulfuric acid;

Reference yield:

: 6809-91-2
1-cyanobenzocyclobutane

: 61599-85-7
bicyclo[4.2.0]octa-1,3,5-trien-7-amine

Guidance literature:: Multi-step reaction with 2 steps

1: (alkaline hydrolysis)

2: NaN₃, H₂SO₄ / CHCl₃

With sodium azide; sulfuric acid; In chloroform;
DOI:10.1021/jm00326a026