6-Phenyl-2,2'-bipyridine

Base Information

• Chemical Name: 6-Phenyl-2,2'-bipyridine
• CAS No.: 61633-06-5
• Molecular Formula: C16H12N2
• Molecular Weight: 232.285
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID60404883
• Nikkaji Number: J90.168G
• Wikidata: Q82209223
• Mol file: 61633-06-5.mol

Synonyms:6-phenyl-2,2'-bipyridine

Chemical Property of 6-Phenyl-2,2'-bipyridine

Chemical Property:

• Melting Point: 83.5-84.5 °C(Solv: ligroine (8032-32-4); ethyl ether (60-29-7))
• Boiling Point: 390.3±27.0 °C(Predicted)
• PKA: 4.06±0.22(Predicted)
• PSA: 25.78000
• Density: 1.125±0.06 g/cm3(Predicted)
• LogP: 3.81060
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 232.100048391
• Heavy Atom Count: 18
• Complexity: 248

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC(=CC=C2)C3=CC=CC=N3

Technology Process of 6-Phenyl-2,2'-bipyridine

There total 12 articles about 6-Phenyl-2,2'-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.3%

2-bromo-6-(pyridin-2-yl)pyridine (10495-73-5) + phenylboronic acid (98-80-6) → 6-phenyl-2,2'-bipyridine (61633-06-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In water; toluene; Inert atmosphere; Reflux;

DOI:10.1021/acs.inorgchem.1c01142

Reference yield: 82.0%

iodobenzene (591-50-4) + C10H7ClMgN2 → 6-phenyl-2,2'-bipyridine (61633-06-5)

Guidance literature:

iodobenzene; With TurboGrignard; In tetrahydrofuran; at -40 ℃; for 1h; Inert atmosphere;

With tbepc; In tetrahydrofuran; at -40 - 0 ℃; for 2h; Inert atmosphere;

C₁₀H₇ClMgN₂; Further stages;

DOI:10.1039/c4cc08494b

Reference yield: 71.0%

[2,2]bipyridinyl (366-18-7) + diphenylzinc (1078-58-6) → 6-phenyl-2,2'-bipyridine (61633-06-5)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; tricyclohexylphosphine; In toluene; at 130 ℃; for 20h;

DOI:10.1021/ja9053509

upstream raw materials:

[2,2]bipyridinyl

3-(dimethylamino)propiophenone hydrochloride

1-(2-oxo-2-(2-pyridyl)ethyl)pyridinium iodide

5-<2-Oxo-2-(2-pyridyl)ethyl>-3-phenyl-2-isoxazoline

Downstream raw materials:

bis(6-phenyl-2,2'-bipyridine)copper(I) hexafluorophosphate

Ru((C₅H₄N)2C₅H₂NC₆H₄CH₃)(C₅H₄NC₅H₃NC₆H₅)Cl⁽¹⁺⁾*PF₆^(1-)={Ru((C₅H₄N)2C₅H₂NC₆H₄CH₃)(C₅H₄NC₅H₃NC₆H₅)Cl}PF₆

Ru((C₅H₄N)2C₅H₃N)(C₅H₄NC₅H₃NC₆H₅)Cl⁽¹⁺⁾*PF₆^(1-)={Ru((C₅H₄N)2C₅H₃N)(C₅H₄NC₅H₃NC₆H₅)Cl}PF₆

Ru((C₅H₄N)2C₅H₂NC₆H₅)(C₅H₄NC₅H₃NC₆H₅)Cl⁽¹⁺⁾*PF₆^(1-)={Ru((C₅H₄N)2C₅H₂NC₆H₅)(C₅H₄NC₅H₃NC₆H₅)Cl}PF₆

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 61633-06-5 6-Phenyl-2,2'-bipyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send