1-(4-Methylphenyl)-3-(pyridin-3-ylmethyl)thiourea

Base Information

Chemical Name:1-(4-Methylphenyl)-3-(pyridin-3-ylmethyl)thiourea
CAS No.:6411-19-4
Molecular Formula:C₆H₁₂O₃
Molecular Weight:132.159
Hs Code.:
DSSTox Substance ID:DTXSID80982618
ChEMBL ID:CHEMBL1516983

Synonyms:1-(4-methylphenyl)-3-(pyridin-3-ylmethyl)thiourea;N-(4-methylphenyl)-N'-(3-pyridinylmethyl)thiourea;SMR000194924;Maybridge1_003608;MLS000573422;CHEMBL1516983;HMS551L22;DTXSID80982618;HMS2183O04;STK094150;AKOS002199532;AE-641/00412056;SR-01000233875;SR-01000233875-1;N-(4-Methylphenyl)-N'-[(pyridin-3-yl)methyl]carbamimidothioic acid

Suppliers and Price of 1-(4-Methylphenyl)-3-(pyridin-3-ylmethyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(4-Methylphenyl)-3-(pyridin-3-ylmethyl)thiourea

Chemical Property:

Vapor Pressure:4.14E-07mmHg at 25°C
Boiling Point:415.4°C at 760 mmHg
Flash Point:205°C
Density:1.228g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:257.09866866
Heavy Atom Count:18
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC(=S)NCC2=CN=CC=C2

Technology Process of 1-(4-Methylphenyl)-3-(pyridin-3-ylmethyl)thiourea

There total 4 articles about 1-(4-Methylphenyl)-3-(pyridin-3-ylmethyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 10024-70-1,16510-79-5
3-methoxybutanoic acid

: 74-88-4
methyl iodide

: 6411-19-4
3-Methoxy-2-methyl-buttersaeure

Guidance literature:: 3-methoxybutanoic acid; With lithium diisopropyl amide; In tetrahydrofuran; at -15 ℃; for 0.75h; Inert atmosphere; Sealed tube;

With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; In tetrahydrofuran; at 5 ℃; for 0.5h; Inert atmosphere; Sealed tube;

methyl iodide; Further stages;
DOI:10.1021/ol502377x

Reference yield:

: 1776-39-2
(1-methoxy-ethyl)-methyl-malonic acid diethyl ester

: 6411-19-4
3-Methoxy-2-methyl-buttersaeure

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / aq. ethanol / Heating

2: (heating)

With potassium hydroxide; In ethanol;