2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine

Base Information

Chemical Name:2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine
CAS No.:61655-77-4
Molecular Formula:C9H13ClN4
Molecular Weight:212.682
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40432826
Nikkaji Number:J3.513.681I
Mol file:61655-77-4.mol

Synonyms:2-chloro-6-(4-methylpiperazin-1-yl)pyrazine;61655-77-4;1-(6-CHLORO-2-PYRAZINYL)-4-METHYLPIPERAZINE;Pyrazine, 2-chloro-6-(4-methyl-1-piperazinyl)-;SCHEMBL3056725;DTXSID40432826;ZMVHGTJAFGHEBY-UHFFFAOYSA-N;AMY27544;MFCD12024895;AKOS005264861;MB11477;2-Chloro-6-(4-methylpiperazino)pyrazine;AS-65748;BB 0260921;CS-0151075;FT-0681432;J3.513.681I;D82259;Z729849094;6'-CHLORO-4-METHYL-3,4,5,6-TETRAHYDRO-2H-[1,2']BIPYRAZINYL

Suppliers and Price of 2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-chloro-6-(4-methylpiperazin-1-yl)pyrazine
5mg
$ 45.00

Matrix Scientific
1-(6-Chloro-2-pyrazinyl)-4-methylpiperazine
2.500g
$ 800.00

Matrix Scientific
1-(6-Chloro-2-pyrazinyl)-4-methylpiperazine
500mg
$ 250.00

Matrix Scientific
1-(6-Chloro-2-pyrazinyl)-4-methylpiperazine
1g
$ 400.00

Crysdot
2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine 95+%
5g
$ 446.00

American Custom Chemicals Corporation
1-(6-CHLORO-2-PYRAZINYL)-4-METHYLPIPERAZINE 95.00%
500MG
$ 837.38

American Custom Chemicals Corporation
1-(6-CHLORO-2-PYRAZINYL)-4-METHYLPIPERAZINE 95.00%
2.5G
$ 1468.50

Ambeed
2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine 95+%
1g
$ 72.00

Ambeed
2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine 95+%
5g
$ 255.00

Ambeed
2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine 95+%
250mg
$ 29.00

Total 10 raw suppliers

Chemical Property of 2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine

Chemical Property:

PSA：32.26000
LogP:0.88470
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:212.0828741
Heavy Atom Count:14
Complexity:182

Purity/Quality:

98%min ^*data from raw suppliers

2-chloro-6-(4-methylpiperazin-1-yl)pyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C2=CN=CC(=N2)Cl

Technology Process of 2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine

There total 2 articles about 2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 109-01-3
1-methyl-piperazine

: 4774-14-5
2,6-dichloropyrazine

: 61655-77-4
6'-chloro-4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl

Guidance literature:: 1-methyl-piperazine; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h; Inert atmosphere;

2,6-dichloropyrazine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1002/bkcs.12101

Reference yield: 91.0%

: 61655-77-4
6'-chloro-4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

In N,N-dimethyl-formamide; Inert atmosphere;

Reference yield: 57.0%

: 61655-77-4
6'-chloro-4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl

: 620595-36-0
2-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

: 2-hydroxy-5-(6-(4-methylpiperazin-1-yl)pyrazin-2-yl)benzaldehyde

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In 1,4-dioxane; ethanol; at 120 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1248/cpb.c14-00325