2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine

Base Information

Chemical Name:2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine
CAS No.:616882-61-2
Molecular Formula:C₁₅H₁₄N₂O₄
Molecular Weight:286.287
Hs Code.:
DSSTox Substance ID:DTXSID201183392

Synonyms:SCHEMBL14564432;DTXSID201183392;2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine;616882-61-2

Suppliers and Price of 2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:286.09535693
Heavy Atom Count:21
Complexity:369

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)[N+](=O)[O-])C=CC2=C(N=CC=C2)OC
Isomeric SMILES:COC1=CC(=C(C=C1)[N+](=O)[O-])/C=C/C2=C(N=CC=C2)OC

Technology Process of 2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine

There total 4 articles about 2-Methoxy-3-[(1E)-2-(5-methoxy-2-nitrophenyl)ethenyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: trifluoro-acetic acid 2-(5-methoxy-2-nitro-phenyl)-1-(2-methoxy-pyridin-3-yl)-ethyl ester

: 616882-61-2
2-methoxy-3-[2-(5-methoxy-2-nitrophenyl)-vinyl]pyridine

Guidance literature:: With Isopropyl acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; at 70 ℃; for 1h;
DOI:10.1021/ol035541i

Reference yield:

: 71255-09-9
2-methoxynicotinaldehyde

: 616882-61-2
2-methoxy-3-[2-(5-methoxy-2-nitrophenyl)-vinyl]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: TBAF; isopropyl acetate / tetrahydrofuran / 0.5 h / 20 °C

2: isopropyl acetate / tetrahydrofuran / 1 h / 20 °C

3: 3.08 g / DBU; isopropyl acetate / 1 h / 70 °C

With Isopropyl acetate; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran;
DOI:10.1021/ol035541i

Reference yield:

: 109434-09-5
4-nitro-3-<(trimethylsilyl)methyl>anisole

: 616882-61-2
2-methoxy-3-[2-(5-methoxy-2-nitrophenyl)-vinyl]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: TBAF; isopropyl acetate / tetrahydrofuran / 0.5 h / 20 °C

2: isopropyl acetate / tetrahydrofuran / 1 h / 20 °C

3: 3.08 g / DBU; isopropyl acetate / 1 h / 70 °C

With Isopropyl acetate; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran;
DOI:10.1021/ol035541i