2-Methoxy-3-pyridinecarboxaldehyde

Base Information

Chemical Name:2-Methoxy-3-pyridinecarboxaldehyde
CAS No.:71255-09-9
Molecular Formula:C7H7NO2
Molecular Weight:137.138
Hs Code.:29339900
European Community (EC) Number:628-373-0
DSSTox Substance ID:DTXSID70501579
Nikkaji Number:J273.986K
Wikidata:Q72485755
Mol file:71255-09-9.mol

Synonyms:71255-09-9;2-Methoxynicotinaldehyde;2-Methoxy-3-pyridinecarboxaldehyde;2-Methoxypyridine-3-Carbaldehyde;2-Methoxy-pyridine-3-carbaldehyde;2-Methoxypyridine-3-carboxaldehyde;3-Pyridinecarboxaldehyde,2-methoxy-;2-Methoxy-3-pyridine carboxaldehyde;MFCD04115112;3-PYRIDINECARBOXALDEHYDE, 2-METHOXY-;2-methoxy-3-formyl-pyridine;SCHEMBL209651;2-METHYOXYNICOTINALDEHYDE;DTXSID70501579;PIFFMIDNNWOQLK-UHFFFAOYSA-N;2-Methoxy-3-pyridinecarboxaldenhyde;AKOS009462239;CS-W004144;PB26137;2-Methoxy-3-pyridinecarboxaldehyde, 96%;AC-23260;DS-12865;SY022300;A9343;AM20061734;FT-0641341;EN300-267392;J-509879;Z1079442776

Suppliers and Price of 2-Methoxy-3-pyridinecarboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
2-Methoxy-pyridine-3-carbaldehyde 95%
5g
$ 585.00

J&W Pharmlab
2-Methoxy-pyridine-3-carbaldehyde 95%
25g
$ 1880.00

Matrix Scientific
2-Methoxy-pyridine-3-carbaldehyde
1g
$ 29.00

Matrix Scientific
2-Methoxy-pyridine-3-carbaldehyde
500mg
$ 19.00

Matrix Scientific
2-Methoxy-pyridine-3-carbaldehyde
5g
$ 104.00

Sigma-Aldrich
2-Methoxy-3-pyridinecarboxaldehyde 96%
5g
$ 257.00

Sigma-Aldrich
2-Methoxy-3-pyridinecarboxaldehyde 96%
1g
$ 79.20

SynQuest Laboratories
2-Methoxypyridine-3-carbaldehyde 95%
1 g
$ 85.00

SynQuest Laboratories
2-Methoxypyridine-3-carbaldehyde 95%
250 mg
$ 25.00

SynQuest Laboratories
2-Methoxypyridine-3-carbaldehyde 95%
25 g
$ 1050.00

Total 81 raw suppliers

Chemical Property of 2-Methoxy-3-pyridinecarboxaldehyde

Chemical Property:

Vapor Pressure:0.051mmHg at 25°C
Refractive Index:n20/D 1.5500(lit.)
Boiling Point:235.265 °C at 760 mmHg
PKA:1.60±0.10(Predicted)
Flash Point:96.085 °C
PSA：39.19000
Density:1.159 g/cm³
LogP:0.90270
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Air Sensitive
XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:137.047678466
Heavy Atom Count:10
Complexity:116

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxy-pyridine-3-carbaldehyde 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41-43-36/37/38
Safety Statements: 26-36/37/39-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC=N1)C=O
Uses 2-Methoxy-3-pyridinecarboxaldehyde may be used to synthesize the following:ethyl 5-amino-4-(2-methoxy-3-pyridyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrano[2,3-b]quinoline-3-carboxylate, a potent AChE inhibitorN-hydroxy-2-pyridinone-based arylsulfone containing a Zn-binding group (ZBG) as MMP-2/-9 inhibitor

Technology Process of 2-Methoxy-3-pyridinecarboxaldehyde

There total 10 articles about 2-Methoxy-3-pyridinecarboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 13472-59-8
3-Bromo-2-methoxypyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 71255-09-9
2-methoxynicotinaldehyde

Guidance literature:: 3-Bromo-2-methoxypyridine; With n-butyllithium; isopropylmagnesium chloride; In tetrahydrofuran; hexane; at -2 - 0 ℃; for 0.75h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1055/s-0031-1289687

Reference yield: 69.0%

: 124-41-4
sodium methylate

: 36404-88-3
2-chloro-3-carbaldehydepyridine

: 71255-09-9
2-methoxynicotinaldehyde

Guidance literature:: In methanol; for 5h; Reflux;
DOI:10.1016/j.bmc.2014.12.011

Reference yield: 46.0%

: 2591-86-8
N-Formylpiperidine

: 1628-89-3
2-methoxypyridine

: 71255-09-9
2-methoxynicotinaldehyde

Guidance literature:: 2-methoxypyridine; With methyllithium; diisopropylamine; In tetrahydrofuran; diethyl ether; at -40 - 0 ℃; for 3h;

N-Formylpiperidine; In tetrahydrofuran; diethyl ether; at -40 ℃; for 2h;
DOI:10.1002/hlca.202100211