2-(3-Bromophenyl)-5-chloro-1,3-benzoxazole

Base Information

Chemical Name:2-(3-Bromophenyl)-5-chloro-1,3-benzoxazole
CAS No.:61712-41-2
Molecular Formula:C13H7BrClNO
Molecular Weight:308.562
Hs Code.:
DSSTox Substance ID:DTXSID80359644
Wikidata:Q82140945

Synonyms:2-(3-bromophenyl)-5-chloro-1,3-benzoxazole;61712-41-2;DTXSID80359644;STK259817;AKOS003342169

Suppliers and Price of 2-(3-Bromophenyl)-5-chloro-1,3-benzoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(3-Bromophenyl)-5-chloro-1,3-benzoxazole

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:306.93995
Heavy Atom Count:17
Complexity:278

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)C2=NC3=C(O2)C=CC(=C3)Cl

Technology Process of 2-(3-Bromophenyl)-5-chloro-1,3-benzoxazole

There total 4 articles about 2-(3-Bromophenyl)-5-chloro-1,3-benzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 3132-99-8
m-bromobenzoic aldehyde

: 95-85-2
2-hydroxy-5-chloro-aniline

: 61712-41-2
2-(3-bromophenyl)-5-chlorobenzo[d]oxazole

Guidance literature:: With potassium carbonate; 1-methyl-3-(n-butyl)imidazolium iodide; In o-xylene; para-xylene; m-xylene; at 120 ℃; for 10h; Green chemistry;
DOI:10.1055/s-0036-1591524

Reference yield:

: 1711-09-7
3-bromobenzoyl chloride

: 61712-41-2
2-(3-bromophenyl)-5-chlorobenzo[d]oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / water; diethyl ether / 20 °C

2: iron(III) chloride hexahydrate / toluene / 20 h / 140 °C / Sealed tube

With iron(III) chloride hexahydrate; sodium hydrogencarbonate; In diethyl ether; water; toluene;
DOI:10.1002/adsc.202101359

Reference yield:

: 95-55-6
2-amino-phenol

: 61712-41-2
2-(3-bromophenyl)-5-chlorobenzo[d]oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / water; diethyl ether / 20 °C

2: iron(III) chloride hexahydrate / toluene / 20 h / 140 °C / Sealed tube

With iron(III) chloride hexahydrate; sodium hydrogencarbonate; In diethyl ether; water; toluene;
DOI:10.1002/adsc.202101359