2-Hydroxy-4-methyl-5-nitropyridine

Base Information

Chemical Name:2-Hydroxy-4-methyl-5-nitropyridine
CAS No.:21901-41-7
Molecular Formula:C6H6N2O3
Molecular Weight:154.125
Hs Code.:29337900
European Community (EC) Number:626-040-4
NSC Number:402987
DSSTox Substance ID:DTXSID90323078
Nikkaji Number:J1.183.922C
Wikidata:Q72485421
Mol file:21901-41-7.mol

Synonyms:2-Hydroxy-4-methyl-5-nitropyridine;21901-41-7;4-methyl-5-nitropyridin-2-ol;4-methyl-5-nitro-1H-pyridin-2-one;2-Hydroxy-5-nitro-4-picoline;4-Methyl-5-nitropyridin-2(1H)-one;2-hydroxy-5-nitro-4-methylpyridine;2-hydroxy-4-methyl-5-nitro pyridine;2-hydroxy-5-nitro-4-methyl pyridine;2-Hyrdoxy-4-Methyl-5-Nitropyridine;MFCD00010690;2(1H)-Pyridinone, 4-methyl-5-nitro-;NSC 402987;4-Methyl-5-nitro-2-pyridinol;NSC402987;4-methyl-5-nitro-1,2-dihydropyridin-2-one;5-Nitro-4-picolin-2-ol;SCHEMBL801081;4-Methyl-5-nitro-2-pyridone;4-methyl-5-nitro-pyridin-2-ol;DTXSID90323078;4-Methyl-5-nitro-2-pyridinol #;BCP22138;MFCD01104143;4-Methyl-5-nitro-2(1H)-pyridinone;4-methyl-5-nitro-1H-pyridine-2-one;4-Methyl-5-nitropyridine-2(1H)-one;AKOS005257669;AKOS009156970;AC-7155;CS-W002059;DS-1624;NSC-402987;PB47375;SY004332;2-Hydroxy-4-methyl-5-nitropyridine, 98%;A4689;AM20070019;FT-0638163;FT-0653650;H1050;EN300-51195;W-206686;Z625801054

Suppliers and Price of 2-Hydroxy-4-methyl-5-nitropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyl-5-nitro-1,2-dihydropyridin-2-one
100mg
$ 75.00

TCI Chemical
2-Hydroxy-4-methyl-5-nitropyridine >98.0%(GC)(T)
5g
$ 138.00

TCI Chemical
2-Hydroxy-4-methyl-5-nitropyridine >98.0%(GC)(T)
1g
$ 46.00

Sigma-Aldrich
2-Hydroxy-4-methyl-5-nitropyridine 98%
5g
$ 67.00

Matrix Scientific
2-Hydroxy-4-methyl-5-nitropyridine 98%
100g
$ 178.00

Matrix Scientific
2-Hydroxy-4-methyl-5-nitropyridine 98%
5g
$ 15.00

Matrix Scientific
2-Hydroxy-4-methyl-5-nitropyridine 98%
25g
$ 59.00

Frontier Specialty Chemicals
2-Hydroxy-4-methyl-5-nitropyridine 98%
1g
$ 18.00

Crysdot
2-Hydroxy-4-methyl-5-nitropyridine 95+%
500g
$ 446.00

Chemenu
2-Hydroxy-4-methyl-5-nitropyridine 95%
100g
$ 122.00

Total 98 raw suppliers

Chemical Property of 2-Hydroxy-4-methyl-5-nitropyridine

Chemical Property:

Appearance/Colour:Orange plates
Vapor Pressure:0.00188mmHg at 25°C
Melting Point:186-190 °C(lit.)
Refractive Index:1.608
Boiling Point:292 °C at 760 mmHg
PKA:8.10±0.10(Predicted)
Flash Point:130.4 °C
PSA：78.94000
Density:1.44 g/cm³
LogP:1.52700
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:154.03784206
Heavy Atom Count:11
Complexity:272

Purity/Quality:

99% ^*data from raw suppliers

4-Methyl-5-nitro-1,2-dihydropyridin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn, Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-37/39-36/37/39-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=CC(=O)NC=C1[N+](=O)[O-]

Technology Process of 2-Hydroxy-4-methyl-5-nitropyridine

There total 6 articles about 2-Hydroxy-4-methyl-5-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 6635-90-1
2-Methoxy-4-methyl-5-nitropyridine

: 21901-41-7
2-hydroxy-4-methyl-5-nitropyridine

Guidance literature:: With hydrogen bromide; In acetic acid; at 0 - 60 ℃; for 2h;

Reference yield: 67.2%

: 21901-40-6
2-amino-5-nitro-4-picoline

: 21901-41-7
2-hydroxy-4-methyl-5-nitropyridine

Guidance literature:: With sulfuric acid; sodium nitrite; at -5 - 0 ℃; for 3.16667h;

Reference yield:

: 695-34-1
2-Amino-4-methylpyridine

: 21901-41-7
2-hydroxy-4-methyl-5-nitropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: concentrated H₂SO₄; concentrated HNO₃

2: aqueous sulfuric acid; sodium nitrite / Diazotization

With sulfuric acid; nitric acid; sodium nitrite;
DOI:10.1039/jr9540002448