6635-90-1

Usage

Uses

Used in Organic Synthesis:
2-METHOXY-5-NITRO-4-PICOLINE is used as a key intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-METHOXY-5-NITRO-4-PICOLINE is used as a building block for the development of new drugs. Its presence in the molecular structure can influence the pharmacological properties of the final drug product, contributing to its therapeutic effects and potential applications in treating various diseases and medical conditions.
Used in Agrochemicals:
2-METHOXY-5-NITRO-4-PICOLINE is utilized as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby contributing to increased crop yields and agricultural productivity.
Used in Dyestuff Industry:
In the dyestuff industry, 2-METHOXY-5-NITRO-4-PICOLINE is employed as a raw material for the production of various dyes and pigments. Its chemical properties enable it to contribute to the colorfastness and stability of the dyes, making it an essential component in the creation of high-quality colorants for textiles, plastics, and other applications.

InChI:InChI=1/C7H8N2O3/c1-5-3-7(12-2)8-4-6(5)9(10)11/h3-4H,1-2H3

Upstream product

• 23056-33-9 2-chloro-4-methyl-5-nitro-pyridine 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 

Downstream Products

• 6635-91-2 4-methyl-6-(methyloxy)-3-pyridinamine 
• 21901-41-7 2-hydroxy-4-methyl-5-nitropyridine 
• 17288-43-6 (5-methoxy-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol 
• 17288-36-7 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid 
• 1205747-86-9 2-benzyl-8-methoxy-1,2,3,4,10,10a-hexahydropyrido[4',3':4,5]pyrrolo-[1,2-a]pyrazine 
• 1205748-13-5 N-({2-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1,2,3,4,10,10a-hexahydropyrido[4',3':4,5]pyrrolo[1,2-a]pyrazin-8-yl}carbonyl)-4-({(1R)-3-(dimethyl-amino)-1-[(phenylsulphanyl)methyl]propyl}amino)-3-nitrobenzene-sulphonamide 
• 1205747-90-5 Methyl 2-[(4'-chloro[1,1'-biphenyl]-2-yl)methyl]-1,2,3,4,10,10a-hexahydropyrido[4',3':4,5]pyrrolo[1,2-a]pyrazine-8-carboxylate 
• 1205747-88-1 Methyl 2-benzyl-1,2,3,4,10,10a-hexahydropyrido[4',3':4,5]pyrrolo[1,2-a]-pyrazine-8-carboxylate 
• 1205747-85-8 2-Benzyl-8-methoxy-2,3,10,10a-tetrahydropyrido[4',3':4,5]pyrrolo[1,2-a]-pyrazine-1,4-dione 
• 3469-63-4 5-methoxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Polycyclic compound for inhibiting RNA helicase DHX33

The invention relates to a polycyclic compound for inhibiting RNA helicase DHX33. In particular, the invention relates to a compound shown as a formula I or a pharmaceutically acceptable form thereof, a pharmaceutical composition containing the compound, a preparation method of the compound, and medical application of the compound to prevention and/or treatment of DHX33 related diseases.

TRICYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Compounds of formula (I): wherein: A represents a 5, 6 or 7-membered (hetero)aromatic or non-aromatic ring,Z1, Z2 and Z3 each independently of the others represents a CH group or a nitrogen atom, it being understood that at least one of these three groups is a nitrogen atom,X represents an alkylene chain as defined in the description,R2 represents an aryl or heteroaryl group,the group R1 represents a group of formula (II) as defined in the description Medicinal products containing the same which are useful in treating conditions involving a defect in apoptosis.

TRICYCLIC COMPOUNDS AND USE THEREOF

There is provided a compound of the formula (I′): wherein x is a nitrogen or CRx, Rx is a hydrogen, etc., R1 is an optionally substituted hydrocarbon group, etc., R2 is an optionally substituted hydrocarbon group, etc., ring A is 5- to 8-membered heterocyclic ring, etc., and each of Y1, Y2 and Y3 is an optionally substituted carbon or a nitrogen, etc.; or a salt thereof or a prodrug thereof, which have CRF receptor antagonistic activity and use thereof.

Heterocyclic FXR binding compounds

The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists or partial agonists of the NR1H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds.

5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection

Disclosed are novel 5,11-dihydro-6H-dipyrido[3,2-b; 2',3'-e][1,4]diazepines. These are useful in the prevention or treatment of HIV infection.

Pharmaceutically active 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines

Compounds of the formula STR1 wherein one of A, B, D and E is N and the remaining three atoms are C; R1 and R2 are independently selected from hydrogen and C1 to C6 alkyl; and R3, R4, R5 and R6 are independently selected from hydrogen, halogen, hydroxy, C1 -C6 alkyl, C1 -C8 alkoxy, phenyl-C1 -C6 alkoxy, phenoxy --NR7 R8 wherein R7 and R8 are independently selected from hydrogen, C1 -C8 alkyl, C1 -C6 alkanoyl and COOR9 wherein R9 is hydrogen or C1 -C6 alkyl, cyano, COOR10 wherein R10 is hydrogen or C1 -C6 alkyl, and CONR11 R12 where R10 and R11 are independently selected from hydrogen and C1 -C6 alkyl, and the pharmaceutically acceptable salts thereof. The compounds are useful psychotherapeutics and may be used in treating obesity, depression and disorders wherein aggression is a symptom.