N-(3-Chloro-7-nitro-9-oxo-9H-fluoren-2-yl)acetamide

Base Information

• Chemical Name: N-(3-Chloro-7-nitro-9-oxo-9H-fluoren-2-yl)acetamide
• CAS No.: 7151-60-2
• Molecular Formula: C15H9ClN2O4
• Molecular Weight: 316.696
• DSSTox Substance ID: DTXSID20410884
• NSC Number: 70212
• Wikidata: Q82217230
• Mol file: 7151-60-2.mol

Synonyms:7151-60-2;NSC70212;NCIOpen2_008408;N-(3-Chloro-7-nitro-9-oxo-9H-fluoren-2-yl)acetamide;DTXSID20410884;NSC-70212

Chemical Property of N-(3-Chloro-7-nitro-9-oxo-9H-fluoren-2-yl)acetamide

Chemical Property:

• Vapor Pressure: 9.33E-15mmHg at 25°C
• Boiling Point: 608.6°Cat760mmHg
• Flash Point: 321.9°C
• Density: 1.57g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 316.0250845
• Heavy Atom Count: 22
• Complexity: 506

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)NC1=C(C=C2C3=C(C=C(C=C3)[N+](=O)[O-])C(=O)C2=C1)Cl

Technology Process of N-(3-Chloro-7-nitro-9-oxo-9H-fluoren-2-yl)acetamide

There total 3 articles about N-(3-Chloro-7-nitro-9-oxo-9H-fluoren-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-oxo-2-acetylamino-7-nitrofluorene (7151-59-9) → N-2-(3-Chlor-7-nitro-9-oxo-fluorenyl)-acetamid (7151-60-2)

Guidance literature:

With chlorine; iron(III) chloride;

DOI:10.1021/jm00331a008

Reference yield:

N-(3-chloro-9-oxo-fluoren-2-yl)-acetamide (6633-21-2) → N-2-(3-Chlor-7-nitro-9-oxo-fluorenyl)-acetamid (7151-60-2)

Guidance literature:

With sulfuric acid; nitric acid;

DOI:10.1021/jm00331a008

Reference yield:

2-acetylamino-9-fluorenone (3096-50-2) → N-2-(3-Chlor-7-nitro-9-oxo-fluorenyl)-acetamid (7151-60-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Cl₂, FeCl₃

2: HNO₃, H₂SO₄

With sulfuric acid; nitric acid; chlorine; iron(III) chloride;

DOI:10.1021/jm00331a008

upstream raw materials:

9-oxo-2-acetylamino-7-nitrofluorene

N-(3-chloro-9-oxo-fluoren-2-yl)-acetamide

2-acetylamino-9-fluorenone