3096-50-2

Usage

InChI:InChI=1/C15H11NO2/c1-9(17)16-10-6-7-12-11-4-2-3-5-13(11)15(18)14(12)8-10/h2-8H,1H3,(H,16,17)

Upstream product

• 53-96-3 2-acetylaminofluorene 
• 3096-57-9 2-amino-9-fluorenone 
• 108-24-7 acetic anhydride 
• 57229-41-1 9-Hydroxy-2-acetylaminofluorene 
• 3096-52-4 2-nitro-9H-fluoren-9-one 
• 75-36-5 acetyl chloride 

Downstream Products

• 7151-59-9 9-oxo-2-acetylamino-7-nitrofluorene 
• 13287-73-5 N-2-(3-Nitro-9-oxo-fluorenyl)-acetamid 
• 108973-47-3 2-acetamido-9H-fluoren-9-yl acetate 
• 7151-60-2 N-2-(3-Chlor-7-nitro-9-oxo-fluorenyl)-acetamid 
• 7355-91-1 2-(3.4-Dichlor-benzylidenamino)-3-chlor-9-oxo-fluoren 
• 6966-99-0 2-(2-Chlor-benzylidenamino)-3-chlor-9-oxo-fluoren 
• 7145-64-4 2-(3,4-Dichlor-phenyl)-3-chlor-9-oxo-fluoren 
• 6633-42-7 2,3-diamino-fluoren-9-one 
• 6955-65-3 3-Chlor-9-oxo-2-fluorenamin 
• 2915-84-6 2,7-diaminofluoren-9-one 
• 6942-29-6 N-2-(3.7-Dichlor-9-oxo-fluorenyl)-acetamid 
• 42135-32-0 2-amino-3-nitro-fluoren-9-one 
• 88387-73-9 9-Oxo-2-amino-7-nitrofluorene 
• 6633-21-2 N-(3-chloro-9-oxo-fluoren-2-yl)-acetamide 

Relevant academic research and scientific papers

Benzylic oxygenation of alkylarenes with molecular oxygen in the presence of activated carbon

A variety of alkylarenes such as fluorenes, xanthenes, and anthrone were effectively oxygenated to the corresponding carbonyl compounds with molecular oxygen as oxidant in the presence of activated carbon.

Oxidative transformation of 2-acetylaminofluorene by a chemical model for cytochrome P450: A water-insoluble porphyrin and tert-butyl hydroperoxide

Oxidation of 2-acetylaminofluorene (AAF), a carcinogen, by a chemical model for cytochrome P450 was investigated to identify an active mutagen and elucidate the oxidation pathway. The oxidation system consisted of a water-insoluble tetrakis(pentafluorophenyl)porphyrinatoiron(III) chloride and tert-butyl hydroperoxide. The mutagen derived from AAF by the chemical model was 2-nitro-9-fluorenone (NO2F{double bond, long}O), which was mutagenic in Salmonella typhimurium TA1538. AAF was oxidized initially at position 9 of the fluorene carbon by the chemical model forming 2-acetylamino-9-fluorenol (AAF-OH), and then oxidized further to 2-acetylamino-9-fluorenone (AAF{double bond, long}O) as a major product. Initial oxidation of the nitrogen formed 2-nitrofluorene (NO2F), and further oxidation yielded 2-nitro-9-fluorenol (NO2F-OH) as a minor product. These products, AAF-OH, AAF{double bond, long}O, NO2F, and NO2F-OH, and their presumable common intermediate, N-hydroxy-2-acetylaminofluorene, were oxidized by the chemical model, and the formation of NO2F{double bond, long}O was determined. These results showed that NO2F{double bond, long}O was the mutagen derived from AAF in the presence of the chemical model and was formed via oxidation of N-OH-AAF, NO2F, and NO2F-OH. These results may lead to a new metabolic pathway of AAF.

COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE

This invention is directed to, inter alia, compounds, methods, systems, and compositions for the maintenance, enhancement, and expansion of hematopoietic stem cells derived from one or more sources of CD34+ cells. Sources of CD34+ cells include bone marrow, cord blood, mobilized peripheral blood, and non-mobilized peripheral blood. Also provided herein are compounds of Formula I which are useful in maintaining, enhancing, and expanding of hematopoietic stem cells.

Oxidation of secondary benzylic alcohols to ketones and benzylic oxygenation of alkylarenes with hydrogen peroxide in the presence of activated carbon

A variety of benzylic alcohols were oxidized to the corresponding carbonyl compounds selectively with 30% hydrogen peroxide (H in the presence of activated carbon. Alkylarenes such as fluorenes, xanthenes, and anthrone were also effectively oxygenated to the corresponding carbonyl compounds with 30% Has oxidant in the presence of activated carbon. Georg Thieme Verlag Stuttgart · New York.

A novel catalytic role of molecular iodine in the oxidation of benzylic alcohols: Microwave-assisted reaction

Molecular iodine was used to catalyse the oxidation of several benzylic alcohols to the corresponding ketones under the microwave-irradiated method, and the role of iodine was explored.