1-(2-Chlorophenyl)-3-(4-methylphenyl)urea

Base Information

Chemical Name:1-(2-Chlorophenyl)-3-(4-methylphenyl)urea
CAS No.:13256-69-4
Molecular Formula:C₁₄H₁₃ClN₂O
Molecular Weight:260.723
Hs Code.:
European Community (EC) Number:667-094-9
NSC Number:164166
DSSTox Substance ID:DTXSID00304095
Wikidata:Q82049755
ChEMBL ID:CHEMBL1688062

Synonyms:1-(2-chlorophenyl)-3-(4-methylphenyl)urea;13256-69-4;NSC164166;1-(2-Chlorophenyl)-3-(p-tolyl)urea;Oprea1_696854;SCHEMBL5852172;CHEMBL1688062;DTXSID00304095;AKOS002979937;NSC-164166

Suppliers and Price of 1-(2-Chlorophenyl)-3-(4-methylphenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-(2-Chlorophenyl)-3-(4-methylphenyl)urea

Chemical Property:

Vapor Pressure:0.000868mmHg at 25°C
Boiling Point:304.6°Cat760mmHg
Flash Point:138°C
Density:1.316g/cm³
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:260.0716407
Heavy Atom Count:18
Complexity:277

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC(=O)NC2=CC=CC=C2Cl

Technology Process of 1-(2-Chlorophenyl)-3-(4-methylphenyl)urea

There total 4 articles about 1-(2-Chlorophenyl)-3-(4-methylphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 4083-64-1
Tosyl isocyanate

: 95-51-2
o-chloroaniline

: 13256-69-4
1-p-tosyl-3-(2-chlorophenyl)urea

Guidance literature:: In dichloromethane;
DOI:10.1016/0040-4039(94)88523-0

Reference yield:

: 52867-19-3
diphenyl-N-(p-toluenesulfonyl)selenimide

: 13256-69-4
1-p-tosyl-3-(2-chlorophenyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: PhCN, PdCl₂(PhCN)2 / CH₂Cl₂ / 26252.1 Torr / r.t., 30 min then 50 deg C, 2.5 h

2: 64 percent / CH₂Cl₂

With bis(benzonitrile)palladium(II) dichloride; benzonitrile; In dichloromethane;
DOI:10.1016/0040-4039(94)88523-0