2-(2-phenylethyl)naphthalene￡2 - phenethylnaphthalene

Base Information

• Chemical Name: 2-(2-phenylethyl)naphthalene￡2 - phenethylnaphthalene
• CAS No.: 53342-34-0
• Molecular Formula: C18H16
• Molecular Weight: 232.325
• Mol file: 53342-34-0.mol

Synonyms:Ethane,1-(2-naphthyl)-2-phenyl- (7CI); Naphthalene, 2-phenethyl- (6CI);1-(2-Naphthyl)-2-phenylethane; 1-(b-Naphthyl)-2-phenylethane; NSC 409540

Chemical Property of 2-(2-phenylethyl)naphthalene￡2 - phenethylnaphthalene

Chemical Property:

• Vapor Pressure: 5.25E-05mmHg at 25°C
• Boiling Point: 358.5°Cat760mmHg
• Flash Point: 163.6°C
• PSA: 0.00000
• Density: 1.07g/cm³
• LogP: 4.62500

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-phenylethyl)naphthalene￡2 - phenethylnaphthalene

There total 24 articles about 2-(2-phenylethyl)naphthalene￡2 - phenethylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 2-bromonaphthalene (580-13-2) → 1-(2-naphthyl)-2-phenylethane (53342-34-0)

Guidance literature:

With C₇₈H₆₀Cl₂N₂Pd; iso-butanol; potassium hydroxide; at 80 ℃; for 4h; regioselective reaction;

DOI:10.1021/acs.joc.0c01509

Reference yield: 80.0%

bromobenzene (108-86-1,52753-63-6) + 4,4,5,5-tetramethyl-2-(2-(naphthalen-2-yl)ethyl)-1,3,2-dioxaborolane → 1-(2-naphthyl)-2-phenylethane (53342-34-0)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sodium t-butanolate; ruphos; In water; toluene; at 80 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.organomet.1c00171

Reference yield: 78.0%

2-Methoxynaphthalene (93-04-9) + phenethylmagnesium iodide → 1-(2-naphthyl)-2-phenylethane (53342-34-0)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; 1,2-bis-(dicyclohexylphosphino)ethane; In toluene; at 120 ℃; for 14h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/jacs.6b03253

upstream raw materials:

1-(naphthalen-2-yl)-2-phenylethanone

(+/-)-2-(cyclohexen-(1)-yl-ethynyl)-cis-Δ²-octalin

2-naphthylmethyl benzyl sulfone

2-naphthylacetic phenylacetate

Downstream raw materials:

1-(naphthalen-2-yl)-2-phenylethanone