3-(4-Hydroxyphenyl)propenoic acid benzyl ester

Base Information

• Chemical Name: 3-(4-Hydroxyphenyl)propenoic acid benzyl ester
• CAS No.: 61844-62-0
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Mol file: 61844-62-0.mol

Synonyms:

Chemical Property of 3-(4-Hydroxyphenyl)propenoic acid benzyl ester

Chemical Property:

• PSA: 46.53000
• LogP: 3.14880

Purity/Quality:

Analysis control,98.0% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-Hydroxyphenyl)propenoic acid benzyl ester

There total 7 articles about 3-(4-Hydroxyphenyl)propenoic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

p-Coumaric Acid (7400-08-0,50940-26-6) + benzyl bromide (100-39-0) → 3-(4'-hydroxyphenyl)-(E)-propenoic acid benzyl ester (61844-62-0)

Guidance literature:

With potassium hydrogencarbonate; In N,N-dimethyl-formamide; at 40 ℃;

DOI:10.1081/SCC-200046532

Reference yield: 86.0%

para-coumaric acid (7400-08-0,50940-26-6) + benzyl bromide (100-39-0) → 3-(4'-hydroxyphenyl)-(E)-propenoic acid benzyl ester (61844-62-0)

Guidance literature:

With sodium hydrogencarbonate; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; at 40 ℃; for 0.583333h;

DOI:10.1080/00397910701845480

Reference yield: 83.8%

para-coumaric acid (7400-08-0,50940-26-6) + benzyl bromide (100-39-0) → benzyl 3-(4-hydroxyphenyl)acrylate (61844-62-0,115610-22-5,27727-38-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1021/jf500464k

upstream raw materials:

para-coumaric acid

benzyl chloride

benzyl bromide

p-Coumaric Acid

Downstream raw materials:

4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarboxylic acid 4-((E)-2-benzyloxycarbonyl-vinyl)-phenyl ester

benzyl O-TIPS-para-cumarate

benzyl (E)-3-(4-tert-butyldimethylsilyloxyphenyl)prop-2-enoate