2-nitro-7-bromonaphtho(2.1-b)furan

Base Information

• Chemical Name: 2-nitro-7-bromonaphtho(2.1-b)furan
• CAS No.: 75965-73-0
• Molecular Formula: C12H6 Br N O3
• Molecular Weight: 0
• Mol file: 75965-73-0.mol

Synonyms:2-Nitro-7-bromonaphtho[2,1-b]furan;7-Bromo-2-nitronaphtho[2,1-b]furan; NSC 329224; R 7160

Chemical Property of 2-nitro-7-bromonaphtho(2.1-b)furan

Chemical Property:

• Vapor Pressure: 2.1E-07mmHg at 25°C
• Boiling Point: 436.2°C at 760 mmHg
• Flash Point: 217.6°C
• Density: 1.733g/cm³

Purity/Quality:

99% ^*data from raw suppliers

2-NITRO-7-BROMONAPHTHO(2.1-B)FURAN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-nitro-7-bromonaphtho(2.1-b)furan

There total 2 articles about 2-nitro-7-bromonaphtho(2.1-b)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

bromonitromethane (563-70-2) + 6-Bromo-2-hydroxy-1-naphthaldehyde (53815-56-8) → nitro-2 bromo-7 naphto<2,1-b>furanne (75965-73-0)

Guidance literature:

With potassium carbonate; In water; for 1h; Heating;

Reference yield:

6-bromo-naphthalen-2-ol (15231-91-1) → nitro-2 bromo-7 naphto<2,1-b>furanne (75965-73-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / TiCl₄ / CH₂Cl₂ / 2 h / 5 °C

2: 47 percent / K₂CO₃ / H₂O / 1 h / Heating

With titanium tetrachloride; potassium carbonate; In dichloromethane; water;

Reference yield: 89.0%

nitro-2 bromo-7 naphto<2,1-b>furanne (75965-73-0) + (4-n-nonylphenyl)boronic acid (256383-45-6) → 2-nitro-7-(4-nonylphenyl)naphtho[2,1-b]furan (1192648-49-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; at 90 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.bmc.2009.07.079

upstream raw materials:

bromonitromethane

6-Bromo-2-hydroxy-1-naphthaldehyde

6-bromo-naphthalen-2-ol

Downstream raw materials:

(4-(2-nitronaphtho[2,1-b]furan-7-yl)phenyl)methanol

7-(4-methylphenyl)-2-nitronaphtho[2,1-b]furan

7-(4-methoxyphenyl)-2-nitronaphtho[2,1-b]furan

4-(2-nitronaphtho[2,1-b]furan-7-yl)phenol