Alatamine

Base Information

• Chemical Name: Alatamine
• CAS No.: 41855-33-8
• Molecular Formula: C₄₁H₄₅NO₁₈
• Molecular Weight: 839.804
• Mol file: 41855-33-8.mol

Synonyms:O2-benzoyl-26-hydroxy-O2-deacetyl-evonimine;ent-(111S,7Ξ)-11β,16α,19β,114-tetraacetoxy-12β-benzoyloxy-15,11-epoxy-14,7-dihydroxy-7-methyl-(13βH,17βH)-2,9-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclononaphane-18,3,8-trione;Alatamin;

Chemical Property of Alatamine

Chemical Property:

• Melting Point: 184 - 191 °C (methanol)
• Boiling Point: 893.0±65.0 °C(Predicted)
• PKA: 11.69±0.70(Predicted)
• PSA: 263.75000
• Density: 1.46±0.1 g/cm3(Predicted)
• LogP: 0.90880

Purity/Quality:

Analysis control,HPLC≥98% ^*data from raw suppliers

Alatamine ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Alatamine

There total 1 articles about Alatamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

acetic anhydride (108-24-7) + neoalatamine → alatamine (41855-33-8)

Guidance literature:

With pyridine; for 23h; Ambient temperature;

DOI:10.1016/S0031-9422(00)97709-4

Reference yield:

sodium acetate (127-09-3) + alatamine (41855-33-8) → ent-(111S,7Ξ)-11β,16α,19β,114,7-pentaacetoxy-12β-benzoyloxy-15,11-epoxy-14-hydroxy-7-methyl-(13βH,17βH)-2,9-dioxa-1(12,3)-eudesmana-4(3,2)-pyridina-cyclononaphane-18,3,8-trione

Guidance literature:

With acetic anhydride; at 60 ℃; for 18h;

DOI:10.1016/0040-4020(78)80097-0

Reference yield:

acetic anhydride (108-24-7) + alatamine (41855-33-8) → wilfordine (37239-51-3)

Guidance literature:

Multistep reaction; (i) NaBH₄, DMF, (ii) /BRN= 385737/, Py;

DOI:10.1016/0040-4020(78)80097-0

upstream raw materials:

acetic anhydride

Downstream raw materials:

wilfordine