pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride

Base Information

Chemical Name:pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride
CAS No.:25031-06-5
Molecular Formula:C14 H22 N2O5 S . Cl H
Molecular Weight:366.866
Hs Code.:
Mol file:25031-06-5.mol

pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride

Synonyms:4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-amino-3,3-dimethyl-7-oxo-, hydroxymethyl ester pivalate (ester),monohydrochloride (8CI); Methanediol,6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatepivalate (ester) monohydrochloride (8CI); Pivalic acid, ester withhydroxymethyl 6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,monohydrochloride (8CI); Pivalic acid, hydroxymethyl ester6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatemonohydrochloride (8CI); Pivaloyloxymethyl 6-aminopenicillanate hydrochloride

Suppliers and Price of pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Pivaloyloxymethyl6-AminopenicillanateHydrochloride
500mg
$ 220.00

TRC
Pivaloyloxymethyl6-AminopenicillanateHydrochloride
250mg
$ 120.00

Total 4 raw suppliers

Chemical Property of pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride

Chemical Property:

PSA：124.23000
LogP:1.90620

Purity/Quality:

99% ^*data from raw suppliers

Pivaloyloxymethyl6-AminopenicillanateHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Pivaloyloxymethyl 6-aminopenicillanate hydrochloride is an intermediate in the synthesis of Pivampicillin Hydrochloride, a Semi-synthetic antibiotic related to Penicillin (P223500). Antibacterial.

Technology Process of pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride

There total 2 articles about pivaloyloxymethyl [2S-(2alpha,5alpha,6beta)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 551-16-6
6-Aminopenicillanic Acid

: 18997-19-8
Chloromethyl pivalate

: 25031-06-5
(pivaloyloxy)methyl 6β-aminopenicillanate hydrochloride

Guidance literature:: 6-Aminopenicillanic Acid; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

Chloromethyl pivalate; In N,N-dimethyl-formamide; at 26 - 28 ℃; for 4h;
DOI:10.1016/S0040-4039(01)01319-3