L-Phenylalanine, N-(3-bromopropyl)-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester

Base Information

Chemical Name:L-Phenylalanine, N-(3-bromopropyl)-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester
CAS No.:619306-98-8
Molecular Formula:C19H28BrNO4
Molecular Weight:414.34
Hs Code.:

Synonyms:(S)-N-(3-bromo-propyl)-N-(tert-butoxycarbonyl) phenylalanine ethyl ester;(S)-N-(3-bromo-propyl)-N-(tert-butoxycarbonyl) phenylalanine;

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Phenylalanine, N-(3-bromopropyl)-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester

Chemical Property:

PSA：55.84000
LogP:4.18290

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of L-Phenylalanine, N-(3-bromopropyl)-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester

There total 7 articles about L-Phenylalanine, N-(3-bromopropyl)-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: C₁₉H₂₉NO₅

: 619306-98-8
(S)-N-(3-bromopropyl)-N-(tert-butoxycarbonyl)phenylalanine ethyl ester

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 ℃; for 0.5h;

Reference yield:

: 2-[tert-butoxycarbonyl-(3-hydroxy-propyl)-amino]-3-phenyl-propionic acid ethyl ester

: 619306-98-8
(S)-N-(3-bromopropyl)-N-(tert-butoxycarbonyl)phenylalanine ethyl ester

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1021/ja0378299

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 619306-98-8
(S)-N-(3-bromopropyl)-N-(tert-butoxycarbonyl)phenylalanine ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: i-Pr₂NEt / CH₂Cl₂ / 24 h / 20 °C

2: 1.10 g / CBr₄; PPh₃ / CH₂Cl₂ / 0.5 h / 0 °C

With carbon tetrabromide; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In dichloromethane;
DOI:10.1021/ja0378299