4-amino-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide

Base Information

• Chemical Name: 4-amino-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide
• CAS No.: 3571-94-6
• Molecular Formula: C₁₂H₁₆N₄O₂S₂
• Molecular Weight: 312.417
• Hs Code.: 2935009090
• Mol file: 3571-94-6.mol

Synonyms:Sulfanilamide,N1-(5-isobutyl-1,3,4-thiadiazol-2-yl)- (6CI,8CI); 2-Isobutyl-5-sulfanilamido-1,3,4-thiadiazole;2256 R. P.; IBTD; NSC 509005

Chemical Property of 4-amino-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide

Chemical Property:

• Vapor Pressure: 1.22E-10mmHg at 25°C
• Boiling Point: 513.1°Cat760mmHg
• Flash Point: 264.1°C
• PSA: 134.59000
• Density: 1.401g/cm³
• LogP: 3.85460

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-amino-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide

There total 8 articles about 4-amino-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-5-isobutyl-1,3,4-thiadiazole (52057-89-3) → 4-amino-N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide (3571-94-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: aqueous HCl

With pyridine; hydrogenchloride;

DOI:10.1002/ardp.19512840202

Reference yield:

4-acetylamino-N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide (510735-57-6) → 4-amino-N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide (3571-94-6)

Guidance literature:

With sodium hydroxide;

Reference yield:

p-acetylaminobenzenesulfonyl chloride (121-60-8) → 4-amino-N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide (3571-94-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: aqueous HCl

With pyridine; hydrogenchloride;

DOI:10.1002/ardp.19512840202

upstream raw materials:

4-acetylamino-N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide

2-amino-5-isobutyl-1,3,4-thiadiazole

N-(isobutyl-[1,3,4]thiadiazol-2-yl)-isovaleramide

ethyl 4-(chlorosulfonyl)phenylcarbamate