Thiourea, N-(2-benzoylphenyl)-N'-phenyl-

Base Information

• Chemical Name: Thiourea, N-(2-benzoylphenyl)-N'-phenyl-
• CAS No.: 61964-62-3
• Molecular Formula: C20H16N2OS
• Molecular Weight: 332.426
• DSSTox Substance ID: DTXSID60360531
• Wikidata: Q82142323
• Mol file: 61964-62-3.mol

Synonyms:Thiourea, N-(2-benzoylphenyl)-N'-phenyl-;61964-62-3;Oprea1_233259;DTXSID60360531;AKOS003716040;AB00119685-01;Z45831712

Chemical Property of Thiourea, N-(2-benzoylphenyl)-N'-phenyl-

Chemical Property:

• XLogP3: 5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 332.09833431
• Heavy Atom Count: 24
• Complexity: 427

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC=C2NC(=S)NC3=CC=CC=C3

Technology Process of Thiourea, N-(2-benzoylphenyl)-N'-phenyl-

There total 3 articles about Thiourea, N-(2-benzoylphenyl)-N'-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

phenyl isothiocyanate (103-72-0) + (2-aminophenyl)(phenyl)methanone (2835-77-0) → 1-(2-benzoylphenyl)-3-phenylthiourea (61964-62-3)

Guidance literature:

In dimethyl sulfoxide; at 50 ℃; for 1h;

DOI:10.1039/c9ob00349e

Reference yield:

2-nitrobenzophenone (2243-79-0) → 1-(2-benzoylphenyl)-3-phenylthiourea (61964-62-3)

Guidance literature:

Multi-step reaction with 2 steps

1: alcoholic NaOH-solution; zinc dust

2: beim Schmelzen

With sodium hydroxide; zinc;

DOI:10.1111/j.1475-4991.2000.tb00958.x

Reference yield:

→ 1-(2-benzoylphenyl)-3-phenylthiourea (61964-62-3)

Guidance literature:

2-Amino-benzophenon, Phenyl-isothiocyanat, ohne Lsgm.;

upstream raw materials:

phenyl isothiocyanate

(2-aminophenyl)(phenyl)methanone

2-nitrobenzophenone