4-PHENYLBUTYLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 4-PHENYLBUTYLAMINE HYDROCHLORIDE
• CAS No.: 30684-06-1
• Molecular Formula: C10H15 N . Cl H
• Molecular Weight: 185.697
• Hs Code.: 2921499090
• Mol file: 30684-06-1.mol

Synonyms:Benzenebutanamine,hydrochloride (9CI); Butylamine, 4-phenyl-, hydrochloride (6CI,8CI);4-Phenylbutylamine hydrochloride

Chemical Property of 4-PHENYLBUTYLAMINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0373mmHg at 25°C
• Melting Point: 165oC
• Boiling Point: 240.8°Cat760mmHg
• Flash Point: 101.7°C
• PSA: 26.02000
• Density: g/cm³
• LogP: 3.47030
• Water Solubility.: very faint turbidity

Purity/Quality:

98% ^*data from raw suppliers

4-Phenylbutylamine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-PHENYLBUTYLAMINE HYDROCHLORIDE

There total 4 articles about 4-PHENYLBUTYLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-phenylbutyronitrile (2046-18-6) → 4-phenylbutylamine hydrochloride (30684-06-1)

Guidance literature:

4-phenylbutyronitrile; With ethanol; sodium; In hexane; mineral oil; at 0 ℃; for 0.166667h; Inert atmosphere;

With hydrogenchloride; In diethyl ether; water;

Reference yield: 88.0%

N-benzoyl-4-phenylbutylamine (93406-12-3) + ethylmagnesium bromide (925-90-6) → 4-phenylbutylamine hydrochloride (30684-06-1) + 1-phenyl-propan-1-one (93-55-0)

Guidance literature:

N-benzoyl-4-phenylbutylamine; With 2-fluoropyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 0.5h;

ethylmagnesium bromide; With cerium(III) chloride; In tetrahydrofuran; dichloromethane; at -78 ℃; for 2h;

With hydrogenchloride; In ethyl acetate;

DOI:10.1016/j.cclet.2015.05.033

Reference yield: 72.0%

→ 4-phenylbutylamine hydrochloride (30684-06-1)

Guidance literature:

With water; potassium hydroxide; In ethanol; at 105 ℃; for 0.133333h; Microwave irradiation;

With hydrogenchloride;

upstream raw materials:

4-phenylbutyronitrile

N-benzoyl-4-phenylbutylamine

ethylmagnesium bromide

4-phenyl-1-butylamine

Downstream raw materials:

N-(4-phenylbutyl)acetamide

C₁₀H₁₃⁽²⁾H₂N*ClH

S-{1-[N-(3-Phenyl-butyl)-carboxamidino]-ethyl}-thioschwefelsaeure

S-{[N-(4-Phenyl-butyl)-carboxamidino]-methyl}-thioschwefelsaeure

Refernces

• 1、 -. "A method for the production of primary amines". Paragraph 0222; 0223; 0332; 0333. . Retrieved 2016/10/09.