(3,5-Diphenyl-1,2-oxazol-4-yl)methanol

Base Information

Chemical Name:(3,5-Diphenyl-1,2-oxazol-4-yl)methanol
CAS No.:62033-12-9
Molecular Formula:C₁₆H₁₃NO₂
Molecular Weight:251.285
Hs Code.:
DSSTox Substance ID:DTXSID10490574
Wikidata:Q82334410

Synonyms:62033-12-9;(3,5-Diphenyl-1,2-oxazol-4-yl)methanol;(3,5-diphenylisoxazol-4-yl)methanol;DTXSID10490574

Suppliers and Price of (3,5-Diphenyl-1,2-oxazol-4-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3,5-Diphenyl-1,2-oxazol-4-yl)methanol

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=NO2)C3=CC=CC=C3)CO

Technology Process of (3,5-Diphenyl-1,2-oxazol-4-yl)methanol

There total 7 articles about (3,5-Diphenyl-1,2-oxazol-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89479-71-0
3,5-diphenylisoxazole-4-carbaldehyde

: 62033-12-9
(3,5-diphenyl-isoxazol-4-yl)-methanol

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;
DOI:10.1016/S0040-4020(00)00356-2

Reference yield:

: 873-67-6
benzonitrile oxide

: 104-55-2
3-phenyl-propenal

: 62033-12-9
(3,5-diphenyl-isoxazol-4-yl)-methanol

: 141525-32-8
((4SR,5SR)-3,4-diphenyl-4,5-dihydroisoxazol-5-yl)methanol

: trans-4-hydroxymethyl-3,5-diphenyl-4,5-dihydroisoxazole

Guidance literature:: benzonitrile oxide; 3-phenyl-propenal; In diethyl ether; at 0 - 5 ℃; for 48h;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;
DOI:10.1016/S0040-4020(00)00356-2

Reference yield:

: 873-67-6
benzonitrile oxide

: 62033-12-9
(3,5-diphenyl-isoxazol-4-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 8 percent / diethyl ether / 48 h / 0 - 5 °C

2: NaBH₄ / methanol / 2 h / 20 °C

With sodium tetrahydroborate; In methanol; diethyl ether; 1: Cycloaddition / 2: Reduction;
DOI:10.1016/S0040-4020(00)00356-2