6-Bromo-9-pentofuranosyl-9h-purine

Base Information

Chemical Name:6-Bromo-9-pentofuranosyl-9h-purine
CAS No.:14357-07-4
Molecular Formula:C₁₀H₁₁BrN₄O₄
Molecular Weight:331.126
Hs Code.:
NSC Number:62630
DSSTox Substance ID:DTXSID90289660
Mol file:14357-07-4.mol

Synonyms:14357-07-4;6-bromo-9-pentofuranosyl-9h-purine;NSC62630;NCIOpen2_008127;DTXSID90289660;NSC-62630

Suppliers and Price of 6-Bromo-9-pentofuranosyl-9h-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 14 raw suppliers

Chemical Property of 6-Bromo-9-pentofuranosyl-9h-purine

Chemical Property:

Vapor Pressure:7.21E-17mmHg at 25°C
Boiling Point:632.5°Cat760mmHg
Flash Point:336.3°C
Density:2.3g/cm³
XLogP3:0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:329.99637
Heavy Atom Count:19
Complexity:339

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC2=C(C(=N1)Br)N=CN2C3C(C(C(O3)CO)O)O

Technology Process of 6-Bromo-9-pentofuranosyl-9h-purine

There total 3 articles about 6-Bromo-9-pentofuranosyl-9h-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 74465-47-7
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-bromo-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

: 14357-07-4
6-Bromo-purine riboside

Guidance literature:: With acetyl chloride; In ethanol; at 0 - 10 ℃; for 5h; Inert atmosphere;

Reference yield:

: 7387-57-7,953089-09-3
triacetyladenosine

: 14357-07-4
6-Bromo-purine riboside

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / sodium nitrite; benzyltriethylammonium bromide; dichloroacetic acid / SbBr₃ / various solvent(s) / 25 °C

2: 69 percent / NaOH / H₂O / 25 °C

With dichloro-acetic acid; sodium hydroxide; benzyltriethylammonium bromide; sodium nitrite; antimony(III) bromide; In water;
DOI:10.1021/jo0204101