3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

Base Information

Chemical Name:3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine
CAS No.:62051-95-0
Molecular Formula:C₁₁H₇FN₄
Molecular Weight:214.202
Hs Code.:
ChEMBL ID:CHEMBL3245670
DSSTox Substance ID:DTXSID60498565
Wikidata:Q82348705

Synonyms:62051-95-0;3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine;CHEMBL3245670;DTXSID60498565

Suppliers and Price of 3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

Chemical Property:

PSA：43.60000
LogP:1.95460
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:214.06547440
Heavy Atom Count:16
Complexity:250

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)F)N2C3=C(C=CC=N3)N=N2

Technology Process of 3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

There total 5 articles about 3-(3-Fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70358-36-0
C₁₁H₁₀FN₃

: 62051-95-0
3-(3-fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

Guidance literature:: With hydrogenchloride; sodium nitrite; In dichloromethane; N,N-dimethyl acetamide; water; hexan-1-ol; at 20 ℃; for 0.02h; Inert atmosphere;
DOI:10.1002/anie.201300615

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 62051-95-0
3-(3-fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl acetamide; n-heptan1ol / 0.5 h / 170 °C / Inert atmosphere

2: 5%-palladium/activated carbon; hydrogen / N,N-dimethyl acetamide; dichloromethane; hexan-1-ol / 45 °C / 258.58 Torr / Inert atmosphere

3: hydrogenchloride; sodium nitrite / N,N-dimethyl acetamide; dichloromethane; hexan-1-ol; water / 0.02 h / 20 °C / Inert atmosphere

With hydrogenchloride; 5%-palladium/activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; sodium nitrite; In dichloromethane; n-heptan1ol; N,N-dimethyl acetamide; water; hexan-1-ol;
DOI:10.1002/anie.201300615

Reference yield:

: 372-19-0
meta-fluoroaniline

: 62051-95-0
3-(3-fluorophenyl)-3H-[1,2,3]triazolo[4,5-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl acetamide; n-heptan1ol / 0.5 h / 170 °C / Inert atmosphere

2: 5%-palladium/activated carbon; hydrogen / N,N-dimethyl acetamide; dichloromethane; hexan-1-ol / 45 °C / 258.58 Torr / Inert atmosphere

3: hydrogenchloride; sodium nitrite / N,N-dimethyl acetamide; dichloromethane; hexan-1-ol; water / 0.02 h / 20 °C / Inert atmosphere

With hydrogenchloride; 5%-palladium/activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; sodium nitrite; In dichloromethane; n-heptan1ol; N,N-dimethyl acetamide; water; hexan-1-ol;
DOI:10.1002/anie.201300615