Pipethiadene

Base Information

• Chemical Name: Pipethiadene
• CAS No.: 15053-99-3
• Molecular Formula: C₁₈H₁₉NS₂
• Molecular Weight: 313.488
• Hs Code.: 2934999090
• Mol file: 15053-99-3.mol

Synonyms:Piperidine,1-methyl-4-thieno[2,3-c][2]benzothiepin-4(9H)-ylidene- (8CI,9CI); Thieno[2,3-c][2]benzothiepin,piperidine deriv.; Pipethiaden; Pipethiadene

Chemical Property of Pipethiadene

Chemical Property:

• Vapor Pressure: 4.46E-09mmHg at 25°C
• Melting Point: 155-157 °C(Solv: cyclohexane (110-82-7))
• Boiling Point: 471.9°Cat760mmHg
• PKA: 8.91±0.20(Predicted)
• Flash Point: 239.2°C
• PSA: 56.78000
• Density: 1.238g/cm³
• LogP: 4.81920

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pipethiadene

There total 6 articles about Pipethiadene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-(1-methyl-4-piperidyl)-4,9-dihydrothieno<2,3-c>-2-benzothiepin-4-ol (16220-26-1) → pipethiadene (15053-99-3)

Guidance literature:

With sulfuric acid; In water; for 0.25h; Heating;

DOI:10.1135/cccc19830623

Reference yield: 70.0%

4-(1-ethoxycarbonyl-4-piperidylidene)-4,9-dihydrothieno<2,3-c>-2-benzothiepin (85690-09-1) → pipethiadene (15053-99-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Heating; 1.5 h;

DOI:10.1135/cccc19830623

Reference yield:

4-chloro-1-methylpiperidine (5570-77-4) → pipethiadene (15053-99-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.)Mg 2.)(+)-tartaric acid

2: 88 percent / H₂SO₄ / H₂O / 0.25 h / Heating

With L-Tartaric acid; sulfuric acid; magnesium; In water;

DOI:10.1135/cccc19830623

upstream raw materials:

4-(1-methyl-4-piperidyl)-4,9-dihydrothieno<2,3-c>-2-benzothiepin-4-ol

4-(1-ethoxycarbonyl-4-piperidylidene)-4,9-dihydrothieno<2,3-c>-2-benzothiepin

4-(4-piperidylidene)-4,9-dihydrothieno<2,3-c>-2-benzothiepin

methyl iodide