5-hydroxy-4,7-dimethyl-2H-chromen-2-one

Base Information

Chemical Name:5-hydroxy-4,7-dimethyl-2H-chromen-2-one
CAS No.:6335-27-9
Molecular Formula:C11H10O3
Molecular Weight:190.199
Hs Code.:2932209090
NSC Number:29053
DSSTox Substance ID:DTXSID00212742
Nikkaji Number:J1.143.237I
Wikidata:Q83087935
Mol file:6335-27-9.mol

Synonyms:5-hydroxy-4,7-dimethyl-2H-chromen-2-one;6335-27-9;5-hydroxy-4,7-dimethylchromen-2-one;Coumarin, 4,7-dimethyl-5-hydroxy-;5-hydroxy-4,7-dimethylcoumarin;2H-1-Benzopyran-2-one, 4,7-dimethyl-5-hydroxy-;BRN 0163053;4,7-dimethyl-5-hydroxycoumarin;MFCD00460712;5-18-01-00469 (Beilstein Handbook Reference);NSC29053;SCHEMBL12457526;DTXSID00212742;BBL036341;NSC 29053;NSC-29053;STK368402;AKOS000275974;5-hydroxy-4,7-dimethyl-chromen-2-one;LS-55190;VS-13428;CS-0280375;EU-0000193;EN300-186394;SR-01000389768;SR-01000389768-1;5-Hydroxy-4,7-dimethyl-2H-chromen-2-one, AldrichCPR;F0345-1152

Suppliers and Price of 5-hydroxy-4,7-dimethyl-2H-chromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 5-hydroxy-4,7-dimethyl-2H-chromen-2-one

Chemical Property:

Vapor Pressure:4.86E-06mmHg at 25°C
Melting Point:248 °C
Boiling Point:371.3°Cat760mmHg
PKA:7.61±0.20(Predicted)
Flash Point:167.2°C
PSA：50.44000
Density:1.269g/cm³
LogP:2.11540
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:190.062994177
Heavy Atom Count:14
Complexity:282

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C(=CC(=O)OC2=C1)C)O

Technology Process of 5-hydroxy-4,7-dimethyl-2H-chromen-2-one

There total 4 articles about 5-hydroxy-4,7-dimethyl-2H-chromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 3-acetyl-6-carboethoxy-4,5,7-trimethylcoumarin

: 14002-91-6
4,5,7-trimethylcoumarin

: 6335-27-9
5-hydroxy-4,7-dimethylcoumarin

: 225779-02-2
6-carboxy-4,5,7-trimethylcoumarin

Guidance literature:: With sulfuric acid; at 130 ℃; for 0.333333h;

Reference yield: 8.0%

: 105-45-3
acetoacetic acid methyl ester

: 771-03-9
3-acetyl-4-hydroxy-6-methyl-2H-pyran-2-one

: 6335-27-9
5-hydroxy-4,7-dimethylcoumarin

: 225779-03-3
4,5,7-trimethyl-2-oxo-2H-chromene-6-carboxylic acid methyl ester

Guidance literature:: With sodium hydrogencarbonate; for 8h; Heating;

Reference yield:

: 2524-37-0
ethyl orselinate

: 6335-27-9
5-hydroxy-4,7-dimethylcoumarin

Guidance literature:: Multi-step reaction with 3 steps

1: concentrated sulfuric acid

2: aqueous KOH-solution

3: quinoline; copper-powder

With quinoline; potassium hydroxide; sulfuric acid; copper;