2-Hydroxy-N-(4-nitrophenyl)acetamide

Base Information

Chemical Name:2-Hydroxy-N-(4-nitrophenyl)acetamide
CAS No.:62100-58-7
Molecular Formula:C8H8N2O4
Molecular Weight:196.163
Hs Code.:
DSSTox Substance ID:DTXSID70488659
Wikidata:Q82331462

Synonyms:2-Hydroxy-N-(4-nitrophenyl)acetamide;62100-58-7;SCHEMBL7741358;DTXSID70488659

Suppliers and Price of 2-Hydroxy-N-(4-nitrophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 2-Hydroxy-N-(4-nitrophenyl)acetamide

Chemical Property:

PSA：95.15000
LogP:1.12180
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:196.04840674
Heavy Atom Count:14
Complexity:218

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)CO)[N+](=O)[O-]

Technology Process of 2-Hydroxy-N-(4-nitrophenyl)acetamide

There total 5 articles about 2-Hydroxy-N-(4-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 171416-09-4
Ac-Gca-pNA

: 62100-58-7
Gca-pNA

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; methanol; for 0.166667h;
DOI:10.1039/P19950002115

Reference yield: 53.0%

: 4158-86-5
4-oxo-2,2-dimethyl-1,3-dioxolane

: 100-01-6,104810-17-5
4-nitro-aniline

: 62100-58-7
Gca-pNA

Guidance literature:: In toluene; for 24h; Heating;
DOI:10.1055/s-1985-31460

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 62100-58-7
Gca-pNA

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) SOCl₂, 2.) pyridine / 1.) 1 h, 2.) THF, overnight

2: 80 percent / aq. NaOH / methanol; tetrahydrofuran / 0.17 h

With pyridine; sodium hydroxide; thionyl chloride; In tetrahydrofuran; methanol;
DOI:10.1039/P19950002115