Ac-Gca-pNA

Base Information

• Chemical Name: Ac-Gca-pNA
• CAS No.: 171416-09-4
• Molecular Formula: C₁₀H₁₀N₂O₅
• Molecular Weight: 238.2
• Mol file: 171416-09-4.mol

Synonyms:Ac-Gca-pNA

Chemical Property of Ac-Gca-pNA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ac-Gca-pNA

There total 1 articles about Ac-Gca-pNA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetoxyacetic acid (13831-30-6) + 4-nitro-aniline (100-01-6,104810-17-5) → Ac-Gca-pNA (171416-09-4)

Guidance literature:

With pyridine; thionyl chloride; Yield given. Multistep reaction; 1.) 1 h, 2.) THF, overnight;

DOI:10.1039/P19950002115

Reference yield: 80.0%

Ac-Gca-pNA (171416-09-4) → Gca-pNA (62100-58-7)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; methanol; for 0.166667h;

DOI:10.1039/P19950002115

Reference yield:

2-acetoxy 6-nitro acetanilide + acetoxy-acetic acid anilide (56609-07-5) + Ac-Gca-pNA (171416-09-4) → 2-acetylamino 3-nitro phenol (59820-29-0)

Guidance literature:

With sodium hydroxide; nitric acid; In acetic anhydride;

upstream raw materials:

acetoxyacetic acid

4-nitro-aniline

Downstream raw materials:

Gca-pNA

Boc-L-Pro-Gca-pNA

Boc-Gly-Aib-L-Pro-Gca-pNA

Boc-Gly-L-Iva-L-Pro-Gca-pNA

Refernces