Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide

Base Information

Chemical Name:Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide
CAS No.:62157-95-3
Molecular Formula:C11H12O2S
Molecular Weight:208.281
Hs Code.:
DSSTox Substance ID:DTXSID10548049
Nikkaji Number:J914.188J
Wikidata:Q82426633

Synonyms:62157-95-3;Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide;SCHEMBL11802939;DTXSID10548049;AKOS002681267;3-(4-Methylphenyl)-2,5-dihydro-1H-1lambda~6~-thiophene-1,1-dione

Suppliers and Price of Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:208.05580079
Heavy Atom Count:14
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CCS(=O)(=O)C2

Technology Process of Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide

There total 5 articles about Thiophene, 2,5-dihydro-3-(4-methylphenyl)-, 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.8%

: 77-79-2
3-Sulfolene

: 624-31-7
4-tolyl iodide

: 62157-95-3
3-p-Tolyl-2,5-dihydrothiophendioxid

Guidance literature:: With triethylamine; palladium diacetate; tetrabutylammomium bromide; In benzene; for 95h; Ambient temperature;
DOI:10.1016/S0040-4039(00)95764-2

Reference yield: 52.0%

: 624-31-7
4-tolyl iodide

: 157141-28-1
3-(tributylstannyl)-3-sulfolene

: 62157-95-3
3-p-Tolyl-2,5-dihydrothiophendioxid

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 80 ℃; for 12h;
DOI:10.1055/s-1997-1020

Reference yield:

: 459-44-9
4-methylbenzenediazonium tetrafluoroborate

: 62157-95-3
3-p-Tolyl-2,5-dihydrothiophendioxid

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate / methanol / 1 h / 50 °C

2: triethylamine / dichloromethane / Reflux

With palladium diacetate; triethylamine; In methanol; dichloromethane;
DOI:10.1016/j.mencom.2021.07.037