ethyl piperidin-2-ylacetate

Base Information

• Chemical Name: ethyl piperidin-2-ylacetate
• CAS No.: 7511-13-9
• Molecular Formula: C9H17NO2
• Molecular Weight: 207.7

Synonyms:

Chemical Property of ethyl piperidin-2-ylacetate

Chemical Property:

• Vapor Pressure: 0.0577mmHg at 25°C
• Boiling Point: 232.8°Cat760mmHg
• Flash Point: 94.6°C
• Density: 0.969g/cm³

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl piperidin-2-ylacetate

There total 1 articles about ethyl piperidin-2-ylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 2-(pyridinyl-2)acetate (2739-98-2) → piperidine-2-acetic acid ethyl ester hydrochloride (7511-13-9)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; chloroform; at 40 ℃; under 6000.6 Torr;

Reference yield: 71.0%

piperidine-2-acetic acid ethyl ester hydrochloride (7511-13-9) + trifluoromethanesulfonic acid 6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl ester (1334406-60-8) → [1-(6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)piperidin-2-yl]acetic acid ethyl ester (1334406-66-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

piperidine-2-acetic acid ethyl ester hydrochloride (7511-13-9) + 3-(Trifluoromethyl)benzenesulfonyl chloride (777-44-6) → ethyl 2-(1-(3-(trifluoromethyl)-phenylsulfonyl)-piperidin-2-yl)acetate (1174068-37-1)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

upstream raw materials:

ethyl 2-(pyridinyl-2)acetate

Downstream raw materials:

ethyl 2-(1-(3-(trifluoromethyl)-phenylsulfonyl)-piperidin-2-yl)acetate

tert-butyl ({(2S)-1-[(4-methoxy-2,6-dimethylphenyl)sulfonyl]piperidin-2-yl}methoxy)acetate

[1-(6-{tert-butoxycarbonyl-[2-(4-trifluoromethoxyphenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)piperidin-2-yl]acetic acid ethyl ester

2-[1-[[3-(Trifluoromethyl)phenyl]sulfonyl]-piperidin-2-yl]-acetic acid

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