Acetamide, N-(3-phenylbenzo[b]thien-2-yl)-

Base Information

Chemical Name:Acetamide, N-(3-phenylbenzo[b]thien-2-yl)-
CAS No.:62218-75-1
Molecular Formula:C16H13NOS
Molecular Weight:267.351
Hs Code.:
DSSTox Substance ID:DTXSID20442524
Nikkaji Number:J1.290.164J
Wikidata:Q82259838

Synonyms:Acetamide, N-(3-phenylbenzo[b]thien-2-yl)-;62218-75-1;DTXSID20442524;N-[3-Phenylbenzo[b]thiophene-2-yl]acetamide

Suppliers and Price of Acetamide, N-(3-phenylbenzo[b]thien-2-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetamide, N-(3-phenylbenzo[b]thien-2-yl)-

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:267.07178521
Heavy Atom Count:19
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1=C(C2=CC=CC=C2S1)C3=CC=CC=C3

Technology Process of Acetamide, N-(3-phenylbenzo[b]thien-2-yl)-

There total 8 articles about Acetamide, N-(3-phenylbenzo[b]thien-2-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 247163-67-3
1-(3-phenyl-benzo[b]thiophen-2-yl)-ethanone oxime

: 62218-75-1
N-(3-phenylbenzo[b]thiophen-2-yl)acetamide

Guidance literature:: With PPA; In toluene; Heating;
DOI:10.1002/1099-0690(200004)2000:7<1353::AID-EJOC1353>3.0.CO;2-A

Reference yield:

: 10135-00-9
3-bromobenzo[b]thiophene-2-carbaldehyde

: 62218-75-1
N-(3-phenylbenzo[b]thiophen-2-yl)acetamide

Guidance literature:: Multi-step reaction with 6 steps

1: 82 percent / LiCl; CuBr₂ / Pd(PPh₃)4 / dioxane / Heating

2: 95 percent / NaClO₂; NaH₂PO₄; H₂O₂ / H₂O; acetonitrile / 10 °C

3: SOCl₂ / CH₂Cl₂ / 1 h / Heating

4: NaN₃ / acetone; H₂O / 0.33 h / 0 °C

5: dimethylformamide / 2 h / 110 °C

6: pyridine / 20 °C

With pyridine; sodium chlorite; sodium dihydrogenphosphate; thionyl chloride; sodium azide; dihydrogen peroxide; lithium chloride; copper(ll) bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; acetone; acetonitrile; 1: Arylation / 2: Oxidation / 3: Chlorination / 4: Azidation / 5: Hydrolysis / 6: Acetylation;
DOI:10.1002/1099-0690(200004)2000:7<1353::AID-EJOC1353>3.0.CO;2-A

Reference yield:

: 960-16-7
tributylphenylstannane

: 62218-75-1
N-(3-phenylbenzo[b]thiophen-2-yl)acetamide

Guidance literature:: Multi-step reaction with 6 steps

1: 82 percent / LiCl; CuBr₂ / Pd(PPh₃)4 / dioxane / Heating

2: 95 percent / NaClO₂; NaH₂PO₄; H₂O₂ / H₂O; acetonitrile / 10 °C

3: SOCl₂ / CH₂Cl₂ / 1 h / Heating

4: NaN₃ / acetone; H₂O / 0.33 h / 0 °C

5: dimethylformamide / 2 h / 110 °C

6: pyridine / 20 °C

With pyridine; sodium chlorite; sodium dihydrogenphosphate; thionyl chloride; sodium azide; dihydrogen peroxide; lithium chloride; copper(ll) bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; acetone; acetonitrile; 1: Arylation / 2: Oxidation / 3: Chlorination / 4: Azidation / 5: Hydrolysis / 6: Acetylation;
DOI:10.1002/1099-0690(200004)2000:7<1353::AID-EJOC1353>3.0.CO;2-A