(-)-4-Hydroxynorephedrin

Base Information Edit

Chemical Name:(-)-4-Hydroxynorephedrin
CAS No.:771-91-5
Molecular Formula:C₉H₁₃NO₂
Molecular Weight:167.208
Hs Code.:
UNII:O6914L7189
Nikkaji Number:J283.232A
ChEMBL ID:CHEMBL1160700
Mol file:771-91-5.mol

Synonyms:(-)-4-Hydroxynorephedrin;771-91-5;UNII-O6914L7189;O6914L7189;4-[(1R,2S)-2-amino-1-hydroxypropyl]phenol;4-hydroxynorephedrine;Benzenemethanol, alpha-(1-aminoethyl)-4-hydroxy-, (R-(R*,S*))-;(1R,2S)-2-Amino-1-(4-hydroxyphenyl)propan-1-ol;Benzyl alcohol, .alpha.-(1-aminoethyl)-p-hydroxy-, (-)-erythro-;4-((1R,2S)-2-amino-1-hydroxypropyl)phenol;(-)-4-hydroxynorephedrine;SCHEMBL2252628;Benzenemethanol, .alpha.-(1-aminoethyl)-4-hydroxy-, [R-(R*,S*)]-;CHEMBL1160700;NOREPHEDRINE, P-HYDROXY-;(-)-P-HYDROXYNOREPHEDRINE;CHEBI:193721;JAYBQRKXEFDRER-RCOVLWMOSA-N;4-[(1R,2S)-2-amino-1-hydroxypropyl]-phenol;4-((2S)-2-amino-(1R)-1-hydroxypropyl)phenol;(1r,2s)-1-(4-hydroxyphenyl)-2-amino-1-propanol;(1R, 2S)-2-amino-1-(4-hydroxyphenyl)propan-1-ol;(1R,2S)-2-amino-1-(4-hydroxyphenyl)-propan-1-ol;BENZENEMETHANOL, .ALPHA.-((1S)-1-AMINOETHYL)-4-HYDROXY-, (.ALPHA.R)-

Suppliers and Price of (-)-4-Hydroxynorephedrin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (-)-4-Hydroxynorephedrin Edit

Chemical Property:

Melting Point:165-166 °C
Boiling Point:357.9±27.0 °C(Predicted)
PKA:9.96±0.26(Predicted)
PSA：66.48000
Density:1.198g/cm³
LogP:1.47310
XLogP3:0.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:167.094628657
Heavy Atom Count:12
Complexity:133

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C1=CC=C(C=C1)O)O)N
Isomeric SMILES:C[C@@H]([C@@H](C1=CC=C(C=C1)O)O)N

Technology Process of (-)-4-Hydroxynorephedrin

There total 18 articles about (-)-4-Hydroxynorephedrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 635304-44-8
(1R, 2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanol

: 552-85-2,771-91-5,1926-72-3,13104-32-0,37692-93-6,52446-53-4,62928-85-2,62928-86-3,73027-12-0
4-((1R,2S)-2-amino-1-hydroxypropyl)phenol

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; ethanol; at 35 ℃; for 144h; under 2280.15 Torr; Product distribution / selectivity;

Reference yield: 89.0%

: 635304-65-3
(2S)-1-(4-hydroxyphenyl)-2-[((1R)-phenylethyl)amino]-1-propanone

: 552-85-2,771-91-5,1926-72-3,13104-32-0,37692-93-6,52446-53-4,62928-85-2,62928-86-3,73027-12-0
4-((1R,2S)-2-amino-1-hydroxypropyl)phenol

Guidance literature:: With hydrogen; palladium(II) hydroxide/carbon; In ethanol; water; at 40 ℃; for 72h; under 760.051 Torr;

Reference yield: 87.0%

: 635304-39-1
(2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanone methanesulfonate

: 552-85-2,771-91-5,1926-72-3,13104-32-0,37692-93-6,52446-53-4,62928-85-2,62928-86-3,73027-12-0
4-((1R,2S)-2-amino-1-hydroxypropyl)phenol

Guidance literature:: (2S)-1-[4-(benzyloxy)phenyl]-2-[((1R)-phenylethyl)amino]-1-propanone methanesulfonate; With sodium hydrogencarbonate; In water; ethyl acetate;

With hydrogen; palladium(II) hydroxide/carbon; In ethanol; water; at 15 ℃; for 120h; under 760.051 Torr; Product distribution / selectivity;