1-(4-Nitrophenyl)-3,4-dihydroisoquinoline

Base Information

Chemical Name:1-(4-Nitrophenyl)-3,4-dihydroisoquinoline
CAS No.:62333-69-1
Molecular Formula:C15H12N2O2
Molecular Weight:252.272
Hs Code.:
DSSTox Substance ID:DTXSID60500839
Wikidata:Q82352801

Synonyms:1-(4-nitrophenyl)-3,4-dihydroisoquinoline;62333-69-1;SCHEMBL6716592;DTXSID60500839

Suppliers and Price of 1-(4-Nitrophenyl)-3,4-dihydroisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(4-Nitrophenyl)-3,4-dihydroisoquinoline

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:252.089877630
Heavy Atom Count:19
Complexity:367

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN=C(C2=CC=CC=C21)C3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 1-(4-Nitrophenyl)-3,4-dihydroisoquinoline

There total 5 articles about 1-(4-Nitrophenyl)-3,4-dihydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 62497-65-8
4-nitro-N-phenethylbenzamide

: 62333-69-1
p-nitrophenyl-1 dihydro-3,4 isoquinoleine

Guidance literature:: With phosphorus pentoxide; phosphoric acid; at 170 ℃; for 1h;
DOI:10.1039/d0cc01969k

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 62333-69-1
p-nitrophenyl-1 dihydro-3,4 isoquinoleine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine

2: phosphorus (V)-oxide; tetralin

With pyridine; tetralin; phosphorus pentoxide;
DOI:10.1039/jr9490000696

Reference yield:

: 64-04-0
phenethylamine

: 62333-69-1
p-nitrophenyl-1 dihydro-3,4 isoquinoleine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / dichloromethane; water / 0.17 h / 0 °C

2: phosphorus pentoxide; phosphoric acid / 1 h / 170 °C

With phosphorus pentoxide; phosphoric acid; sodium hydroxide; In dichloromethane; water;
DOI:10.1039/d0cc01969k